C20orf79 Inhibitors
SCP2 sterol binding domain containing 1 (SCP2D1) is a protein that is characterized by its ability to bind sterol molecules. As part of the sterol carrier protein family, SCP2D1 plays a role in the intracellular transport of lipids, particularly sterols and other hydrophobic molecules. The transport of these molecules is critical for various biological processes, including membrane biogenesis, lipid metabolism, and the synthesis of steroid hormones.SCP2D1 contains a domain that is homologous to the sterol carrier protein 2 (SCP2), which is known for its role in the shuttling of cholesterol and other lipids between cellular membranes. The sterol-binding domain of SCP2D1 facilitates the transfer of sterols across the aqueous environment of the cytoplasm, thereby influencing the distribution and homeostasis of sterols within the cell.
The protein is essential for maintaining the balance of cholesterol and other sterols within cells, which is vital for cell membrane integrity and function. Abnormal levels of cholesterol and sterols can lead to a variety of diseases, including atherosclerosis and other cardiovascular diseases. SCP2D1 may also be involved in the metabolism of fatty acids and the activation of peroxisome proliferator-activated receptors (PPARs), which are nuclear receptors that play a significant role in lipid metabolism and energy homeostasis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $31.00 $89.00 $135.00 $443.00 | 13 | |
Statins inhibit HMG-CoA reductase, a key enzyme in cholesterol synthesis, potentially influencing SCP2D1-related lipid metabolism. | ||||||
Ezetimibe | 163222-33-1 | sc-205690 sc-205690A | 25 mg 100 mg | $96.00 $241.00 | 12 | |
Ezetimibe targets the Niemann-Pick C1-like 1 protein, affecting cholesterol absorption and potentially impacting SCP2D1 functions. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $41.00 | 9 | |
Fenofibrate activates PPARα receptors, influencing lipid metabolism, which could indirectly affect SCP2D1 activity. | ||||||
Progesterone | 57-83-0 | sc-296138A sc-296138 sc-296138B | 1 g 5 g 50 g | $20.00 $52.00 $298.00 | 3 | |
Progesterone can influence lipid metabolism and cholesterol synthesis, potentially impacting SCP2D1 functions. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $62.00 $124.00 | 1 | |
Niacin affects lipid metabolism, particularly in reducing LDL cholesterol and triglycerides, which might influence SCP2D1 activity. | ||||||
CHOLESTYRAMINE RESIN | 11041-12-6 | sc-507509 | 5 g | $210.00 | ||
Cholestyramine binds bile acids in the intestine, affecting cholesterol metabolism, potentially impacting SCP2D1. | ||||||
Clofibrate | 637-07-0 | sc-200721 | 1 g | $33.00 | ||
Clofibrate, a fibric acid derivative, alters lipid metabolism and may influence SCP2D1 activity. | ||||||
Gemfibrozil | 25812-30-0 | sc-204764 sc-204764A | 5 g 25 g | $66.00 $267.00 | 2 | |
Gemfibrozil, another fibrate, affects lipid metabolism, potentially influencing SCP2D1 functions. | ||||||
R-848 | 144875-48-9 | sc-203231 sc-203231A sc-203231B sc-203231C | 5 mg 25 mg 100 mg 500 mg | $102.00 $306.00 $510.00 $1559.00 | 12 | |
Mipomersen, an antisense oligonucleotide, lowers LDL cholesterol levels and may indirectly affect SCP2D1. | ||||||
Atorvastatin | 134523-00-5 | sc-337542A sc-337542 | 50 mg 100 mg | $257.00 $505.00 | 9 | |
Atorvastatin, a statin, inhibits cholesterol synthesis and may influence SCP2D1's role in lipid metabolism. | ||||||