Maestro Heat-Like Repeat Family Member 8 (MROH8) is a protein encoded by the MROH8 gene in humans. Although the full range of functions of MROH8 is not entirely understood, it belongs to a family of proteins characterized by the presence of maestro heat-like repeats (MROH). These repeat motifs are thought to be involved in protein-protein interactions, which are crucial for various cellular processes.MROH8 is expressed in several tissues, with a higher expression profile in the brain and testes, suggesting a potential role in the neurological system and reproductive function. The precise cellular functions of MROH8 remain to be fully elucidated; however, proteins with similar MROH domains have been implicated in the regulation of signal transduction pathways, vesicle trafficking, and membrane dynamics.
Structurally, MROH8 contains multiple tandem repeats that are typical of the MROH family, which may facilitate complex formation with other proteins. These interactions can potentially influence intracellular signaling cascades and impact the regulation of cellular growth, differentiation, and apoptosis.Due to its expression pattern and structural features, MROH8 is hypothesized to participate in critical developmental processes and could be especially important in the context of neuronal development and spermatogenesis. Genetic studies have hinted at the importance of MROH8, with mutations or disruptions in the MROH8 gene potentially linked to developmental disorders or diseases; however, direct associations and functional consequences are not yet clearly defined.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits the mTOR pathway, which is involved in cell growth and metabolism, potentially influencing MROH8. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Metformin activates AMP-activated protein kinase (AMPK) and may impact MROH8 through metabolic pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is an inhibitor of phosphoinositide 3-kinases (PI3K) and might affect MROH8 by modulating PI3K/AKT signaling. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is an inhibitor of MEK, a key component of the MAPK/ERK pathway, potentially affecting MROH8. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
TSA, an inhibitor of histone deacetylases, affects gene expression and chromatin remodeling, potentially influencing MROH8. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002, a PI3K inhibitor, could affect MROH8 activity by modulating PI3K/AKT signaling. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, with its anti-inflammatory and antioxidant properties, might impact MROH8 indirectly through these mechanisms. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580, a p38 MAPK inhibitor, could influence MROH8 activity by affecting stress response pathways. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
2-Deoxy-D-glucose, a glycolysis inhibitor, might affect MROH8 through metabolic stress pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059, an inhibitor of MEK/ERK, could potentially impact MROH8 through MAPK signaling. | ||||||