C19orf26 Inhibitors
C19orf26 inhibitors encompass a range of chemicals that interfere with specific signaling pathways or cellular processes that C19orf26 is involved in, even though they are not direct inhibitors of C19orf26 itself. These compounds exert their influence by hindering various upstream regulators or essential signals required for the functional activity of C19orf26. For instance, protein kinase C is critical for numerous signaling cascades, and Staurosporine, by inhibiting this kinase, could prevent the phosphorylation-dependent regulation of C19orf26, assuming that its function is contingent upon such post-translational modifications. Similarly, LY294002 and Wortmannin, by targeting PI3K, can lead to the suppression of AKT signaling, which is fundamental to cell survival and proliferation. If C19orf26 operates within these or related pathways, its activity would be expected to decrease as a consequence of PI3K/AKT pathway inhibition.
On the other hand, inhibitors like U0126 and PD98059 specifically target the MEK/ERK pathway, a pivotal signaling axis involved in cell differentiation, growth, and survival. The suppression of this pathway can indirectly result in the functional inhibition of C19orf26 if it is part of the downstream signaling cascade. Additionally, bortezomib's roleC19orf26 inhibitors encompass a range of chemicals that interfere with specific signaling pathways or cellular processes that C19orf26 is involved in, even though they are not direct inhibitors of C19orf26 itself. These compounds exert their influence by hindering various upstream regulators or essential signals required for the functional activity of C19orf26. For instance, protein kinase C is critical for numerous signaling cascades, and Staurosporine, by inhibiting this kinase, could prevent the phosphorylation-dependent regulation of C19orf26, assuming that its function is contingent upon such post-translational modifications. Similarly, LY294002 and Wortmannin, by targeting PI3K, can lead to the suppression of AKT signaling, which is fundamental to cell survival and proliferation. If C19orf26 operates within these or related pathways, its activity would be expected to decrease as a consequence of PI3K/AKT pathway inhibition.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent protein kinase C inhibitor that disrupts signal transduction pathways. Inhibition of protein kinase C can reduce phosphorylation events that C19orf26 may rely on for proper localization or function within the cell. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A phosphoinositide 3-kinase inhibitor that can diminish AKT signaling. As AKT signaling is crucial for cell survival and growth, its inhibition can attenuate processes that C19orf26 may be involved in, particularly if C19orf26 functions in pathways downstream of PI3K/AKT. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, which can lead to the down-regulation of inflammatory responses and other p38 MAPK-dependent signaling pathways. If C19orf26 operates downstream of p38 in any capacity, its activity would be lessened by SB203580. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can suppress cell growth and proliferation. Given that mTOR signaling is a central node in many cellular processes, C19orf26 activity could be diminished due to the broad effects of mTOR inhibition. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that can lead to the buildup of misfolded proteins and disrupt cellular homeostasis. If C19orf26 is involved in proteostasis, its function may be indirectly inhibited due to proteasome blockade. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A specific inhibitor of MEK that prevents its activation of ERK. If C19orf26 acts downstream of the MEK/ERK pathway, PD98059 would reduce its activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $65.00 $267.00 | 257 | |
An inhibitor of the JNK signaling pathway. By inhibiting JNK, SP600125 can alter transcription factor activation and gene expression, which could include genes that regulate C19orf26 or its partners. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor, similar to LY294002, that impairs AKT signaling. It can lead to reduced cell proliferation and survival, potentially affecting cellular processes involving C19orf26. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Specific inhibitor of NF-κB activation, impacting various cellular responses including inflammation and apoptosis. If C19orf26 is involved in any NF-κB mediated process, its activity would be inhibited. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
A hedgehog signaling pathway inhibitor that can prevent the cellular response to hedgehog ligand. If C19orf26 is implicated in the hedgehog pathway, its activity would be reduced by Cyclopamine. | ||||||