C18orf18, or Chromosome 18 Open Reading Frame 18, is a gene that encodes a protein in humans. Positioned on chromosome 18, more specifically at locus 18q21.1, the protein produced by this gene is part of the extensive catalogue of human proteins. The function of the C18orf18 protein, as with many open reading frames discovered via genomic sequencing, is not fully established, which is often the case with proteins found in sequences identified bioinformatically as potential gene products.The protein encoded by C18orf18 may participate in various intracellular processes, which could include roles in cellular metabolism, signal transduction, or gene regulation. Proteins with unknown functions, like C18orf18, often become subjects of research to determine their part in the complex network of cellular activities.
Experimental approaches such as transcriptomics, proteomics, and interaction mapping are typically employed to investigate the physiological role of proteins like C18orf18. By examining its expression patterns across different tissues, the conditions that modulate its expression, and any potential associations with disease phenotypes, researchers can begin to piece together its biological significance.Furthermore, the study of C18orf18's interactions with other proteins or nucleic acids could provide clues about its function. For instance, if C18orf18 is found to interact with proteins involved in cell cycle regulation, it may suggest a role in cell proliferation or maintenance. Alternatively, if it binds to specific DNA sequences, it might imply a regulatory function in gene expression.As the scientific community continues to investigate, data on C18orf18 will help to clarify its function. Each discovery contributes to the broader understanding of the genetic and molecular context of chromosome 18, potentially shedding light on how C18orf18 and similar proteins influence human health and contribute to the pathogenesis of various diseases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Triptolide inhibits RNA polymerase II, potentially reducing C18orf18 transcription. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
α-Amanitin binds to RNA polymerase II, possibly decreasing C18orf18 mRNA synthesis. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates DNA and may prevent C18orf18 gene transcription. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
Cordycepin terminates mRNA elongation, which could limit C18orf18 mRNA accumulation. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
DRB inhibits RNA polymerase II transcription elongation, potentially affecting C18orf18 expression. | ||||||
Flavopiridol Hydrochloride | 131740-09-5 | sc-207687 | 10 mg | $311.00 | ||
Flavopiridol inhibits cyclin-dependent kinases, possibly reducing C18orf18 transcription. | ||||||
Oxaliplatin | 61825-94-3 | sc-202270 sc-202270A | 5 mg 25 mg | $110.00 $386.00 | 8 | |
Oxaliplatin forms DNA adducts, which may impede transcription machinery from accessing C18orf18. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds to DNA and may block C18orf18 gene transcription initiation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A inhibits histone deacetylase, potentially affecting C18orf18 chromatin structure. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine incorporates into RNA, potentially disrupting C18orf18 mRNA synthesis. | ||||||