Date published: 2025-11-1

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C18orf18 Inhibitors

C18orf18, or Chromosome 18 Open Reading Frame 18, is a gene that encodes a protein in humans. Positioned on chromosome 18, more specifically at locus 18q21.1, the protein produced by this gene is part of the extensive catalogue of human proteins. The function of the C18orf18 protein, as with many open reading frames discovered via genomic sequencing, is not fully established, which is often the case with proteins found in sequences identified bioinformatically as potential gene products.The protein encoded by C18orf18 may participate in various intracellular processes, which could include roles in cellular metabolism, signal transduction, or gene regulation. Proteins with unknown functions, like C18orf18, often become subjects of research to determine their part in the complex network of cellular activities.

Experimental approaches such as transcriptomics, proteomics, and interaction mapping are typically employed to investigate the physiological role of proteins like C18orf18. By examining its expression patterns across different tissues, the conditions that modulate its expression, and any potential associations with disease phenotypes, researchers can begin to piece together its biological significance.Furthermore, the study of C18orf18's interactions with other proteins or nucleic acids could provide clues about its function. For instance, if C18orf18 is found to interact with proteins involved in cell cycle regulation, it may suggest a role in cell proliferation or maintenance. Alternatively, if it binds to specific DNA sequences, it might imply a regulatory function in gene expression.As the scientific community continues to investigate, data on C18orf18 will help to clarify its function. Each discovery contributes to the broader understanding of the genetic and molecular context of chromosome 18, potentially shedding light on how C18orf18 and similar proteins influence human health and contribute to the pathogenesis of various diseases.

Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Camptothecin inhibits topoisomerase I, which may reduce C18orf18 transcription.

Leptomycin B

87081-35-4sc-358688
sc-358688A
sc-358688B
50 µg
500 µg
2.5 mg
$105.00
$408.00
$1224.00
35
(2)

Leptomycin B inhibits CRM1/exportin 1, potentially influencing C18orf18 mRNA export and stability.