C14orf38 Inhibitors
Coiled-coil domain containing 175 (CCDC175) is a protein encoded by the CCDC175 gene in humans. As its name suggests, CCDC175 features a coiled-coil domain, which is indicative of a structural motif that mediates protein-protein interactions. These domains consist of alpha-helices that are wound together in a supercoil structure and are fundamental in the formation of various oligomeric states essential for protein function.The specific biological functions of CCDC175 are not extensively characterized. However, proteins with coiled-coil domains are known to be involved in a wide array of cellular processes, including but not limited to, vesicle transport, cell division, and signaling cascades. They often serve as scaffolds or assembly factors that can bring other proteins together to form larger complexes. This structural involvement is crucial for the integrity of multiple cellular components, such as the cytoskeleton, organelle membranes, and the nuclear envelope.
Given the diverse roles that coiled-coil domain-containing proteins play, CCDC175 may be implicated in similar processes, potentially influencing cellular architecture or facilitating intracellular trafficking. Furthermore, the coiled-coil motif could allow CCDC175 to interact with other proteins in a regulatory capacity, modulating their activity or localization within the cell.The expression pattern of CCDC175, as well as any potential post-translational modifications it might undergo, could provide additional insight into its function. Variations in the expression of genes encoding coiled-coil proteins have been associated with certain pathological conditions, including cancers and neurodegenerative diseases. Research into CCDC175 and its interaction partners continues to be important for delineating the precise molecular mechanisms it governs.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
This compound inhibits histone deacetylases (HDAC), which can result in altered chromatin structure and reduced gene expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
It is an inhibitor of DNA methyltransferases, which can lead to hypomethylation of DNA and potential downregulation of gene expression. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
RG108 is another DNA methyltransferase inhibitor, potentially leading to DNA demethylation and gene expression inhibition. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
This compound intercalates into DNA, inhibiting RNA polymerase and thereby preventing mRNA synthesis. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
It binds to GC-rich sequences in the DNA, blocking transcription factor binding and thus gene expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
It is an inhibitor of RNA polymerase II, which is critical for mRNA synthesis of most protein-coding genes. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide inhibits eukaryotic protein synthesis by interfering with the translocation step in the ribosome. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine can inhibit DNA and RNA synthesis by intercalating into nucleic acids, which may decrease gene expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
It inhibits mTOR, which is involved in the regulation of protein synthesis and can lead to a reduction in gene expression. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
This compound displaces BET bromodomain proteins from chromatin, leading to a decrease in gene transcription. | ||||||