Transmembrane protein 273, commonly referred to as TMEM273, is a protein that, as its name suggests, is integrated into the membrane of cells. TMEM273 is encoded by the TMEM273 gene. The "transmembrane" designation indicates that this protein spans the entire lipid bilayer of the cell membrane, with regions exposed to the intracellular environment as well as the extracellular space.The specific functions of TMEM273 are not well-characterized; however, transmembrane proteins typically play crucial roles in various cellular processes. These can include acting as channels or transporters that regulate the movement of ions and molecules across the cell membrane, serving as receptors that bind to ligands and initiate signaling pathways, or functioning in cell adhesion and intercellular communication.
Given its transmembrane nature, TMEM273 may participate in one or more of these functions. Its extracellular domain could be involved in ligand binding or interaction with other cells or the extracellular matrix, while the intracellular domain might interact with the cytoskeleton or relay signals to the cell's interior machinery.Research into TMEM273 might involve determining its expression pattern in different tissues to infer potential functions, investigating the protein's structure to understand how it interacts with other molecules, and studying any genetic variations that could be associated with diseases or conditions.Understanding the role of TMEM273 is significant because transmembrane proteins are often key players in health and disease. They can serve as targets for drugs due to their accessibility from the outside of cells, and their dysfunction can be implicated in a variety of pathological conditions.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
A specific inhibitor of vacuolar type H+-ATPase, could affect TMEM273 by altering endosomal-lysosomal function. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Known for altering endosomal pH, may indirectly influence TMEM273 function by modulating lysosomal activity. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
An inhibitor of N-linked glycosylation, potentially affecting TMEM273 by disrupting protein folding and maturation. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor, could indirectly influence TMEM273 by affecting protein degradation pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor, may impact TMEM273 indirectly by modifying cytoskeletal dynamics and cell morphology. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An inhibitor of MEK, might affect TMEM273 indirectly through the MAPK/ERK pathway. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor, could indirectly affect TMEM273 through the PI3K/Akt signaling pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, potentially affecting TMEM273 expression or function through mTOR signaling pathways. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A MEK1/2 inhibitor, may influence TMEM273 indirectly via the MAPK/ERK pathway. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor, possibly impacting TMEM273 through PI3K/Akt pathway disruption. | ||||||