BTG4 inhibitors encompass a range of compounds primarily chosen due to their potential to target pathways or cellular processes in which BTG4 may play a role. Notably, compounds such as U0126 and LY294002, which target the ERK1/2 and PI3K/Akt pathways respectively, can modulate cellular processes including cell cycle regulation and differentiation. Given BTG4's involvement in cell cycle dynamics, changes to these pathways can indirectly influence its function.
Further, the list includes several CDK inhibitors like Roscovitine, Olomoucine II, and PD0332991. These compounds directly impact cell cycle progression, a realm in which BTG4 operates, signifying potential indirect effects on its function. The regulation of gene expression and protein turnover is another significant domain indirectly linked to BTG4. Inhibitors like Vorinostat (Suberoylanilide Hydroxamic Acid) and 5-Azacytidine that affect gene expression, and Bortezomib that impacts protein degradation, represent key tools in modulating the cellular environment where BTG4 acts. The diversity in this class of inhibitors highlights the intricate network of pathways and processes that can potentially influence BTG4's function and interactions within the cell.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor affecting the Akt signaling pathway. By impacting this pathway, cellular processes related to cell cycle and differentiation can be influenced, indirectly affecting BTG4. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
Cyclin-dependent kinase (CDK) inhibitor. By targeting CDKs, it alters cell cycle progression which can indirectly modulate BTG4 function given its role in cell cycle regulation. | ||||||
Olomoucine | 101622-51-9 | sc-3509 sc-3509A | 5 mg 25 mg | $72.00 $274.00 | 12 | |
Another CDK inhibitor. Affects cell cycle and its associated proteins. BTG4, involved in cell cycle regulation, can be influenced indirectly through alterations in the cell cycle dynamics. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $315.00 | ||
CDK4/6 inhibitor that impacts cell cycle progression. Given BTG4's regulatory role in cell cycle, its function can be indirectly modulated when cell cycle dynamics are altered by such inhibitors. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
MDM2-p53 interaction inhibitor. By stabilizing p53, it affects cell cycle arrest and apoptosis. BTG4, if interacting with components of the p53 pathway, can be indirectly influenced. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor which affects the JNK signaling pathway. If BTG4 has interactions or regulatory roles within the JNK pathway, its function can be indirectly influenced by SP600125. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Proteasome inhibitor impacting protein degradation. By modulating protein turnover, BTG4's stability or interaction with other proteins might be influenced indirectly. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Histone deacetylase inhibitor altering gene expression. If BTG4's function is related to proteins regulated by acetylation, its interactions or stability might be indirectly influenced. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor affecting DNA methylation and gene expression. Changes in gene expression profiles can indirectly affect BTG4's role or interactions within the cell. | ||||||
Plumbagin | 481-42-5 | sc-253283 sc-253283A | 100 mg 250 mg | $51.00 $61.00 | 6 | |
NF-κB pathway inhibitor. If BTG4 operates within or adjacent to the NF-κB pathway, its function can be influenced by changes induced by Plumbagin. | ||||||