Boron trifluoride (BF3) inhibitors, commonly referred to as BTF3 inhibitors, belong to a class of chemical compounds that have garnered significant attention in the field of organic chemistry. These compounds are characterized by their ability to selectively and effectively inhibit various chemical reactions, making them invaluable tools in the realm of synthetic chemistry. BTF3 inhibitors derive their name from the presence of boron trifluoride, a highly reactive and versatile molecule that plays a central role in their structure and function.
The key feature of BTF3 inhibitors lies in their capacity to activate certain chemical transformations that would otherwise be challenging to achieve under normal conditions. This activation occurs through the coordination of boron trifluoride with specific reactants, facilitating the formation of new chemical bonds or the rearrangement of existing ones. The unique reactivity of boron trifluoride allows for the acceleration and control of various reactions, enabling chemists to synthesize complex molecules with precision. Their utility extends beyond traditional synthetic chemistry, as they have also been employed in the preparation of advanced materials for electronics and catalysis, showcasing the versatility and significance of this intriguing class of compounds in the realm of chemical research and innovation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PD 168393 | 194423-15-9 | sc-222138 | 1 mg | $162.00 | 4 | |
PD168393 is an irreversible inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. BTF3 is part of the transcription complex in cells, and while there is no direct inhibition, EGFR signaling can affect transcriptional regulation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a potent inhibitor of phosphoinositide 3-kinases (PI3K). BTF3 may be indirectly affected through PI3K/AKT signaling, which is known to regulate various transcription factors and cellular processes. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a broad-spectrum protein kinase inhibitor. It can indirectly affect BTF3 function by altering the phosphorylation state of transcription factors and other proteins that interact with BTF3 in the transcription complex. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide is a diterpene triepoxide that inhibits the activity of transcription factor NF-κB. As BTF3 is involved in transcriptional regulation, the inhibition of NF-κB can indirectly influence BTF3's role in gene expression. | ||||||
Chelerythrine chloride | 3895-92-9 | sc-3547 sc-3547A | 5 mg 25 mg | $90.00 $317.00 | 17 | |
Chelerythrine is a potent inhibitor of protein kinase C (PKC). It can indirectly affect BTF3 by altering the activity of PKC, which can modulate transcription factors and other proteins that interact with BTF3. | ||||||
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $68.00 $312.00 | 2 | |
Alsterpaullone is a cyclin-dependent kinase (CDK) inhibitor. It may indirectly influence BTF3 by affecting the cell cycle progression and transcription regulation mechanisms that BTF3 is a part of. | ||||||
Oligomycin A | 579-13-5 | sc-201551 sc-201551A sc-201551B sc-201551C sc-201551D | 5 mg 25 mg 100 mg 500 mg 1 g | $179.00 $612.00 $1203.00 $5202.00 $9364.00 | 26 | |
Oligomycin A is an inhibitor of the mitochondrial ATP synthase. It can indirectly affect BTF3 by altering cellular energy levels, which can impact transcriptional processes that BTF3 is involved in. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
MG132 is a proteasome inhibitor. It can indirectly influence BTF3 by preventing the degradation of transcription factors and co-activators that may interact with BTF3, thus affecting transcriptional regulation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Sp600125 is an inhibitor of c-Jun N-terminal kinase (JNK). It may indirectly affect BTF3 by modulating stress response pathways that can influence transcription regulation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is another inhibitor of phosphoinositide 3-kinases (PI3K). It can indirectly affect BTF3 through the PI3K/AKT signaling pathway, which plays a role in transcriptional regulation. | ||||||