BPY2 inhibitors are a class of chemical compounds designed to specifically target and inhibit the BPY2 (Basic Protein, Y-linked 2) protein, a member of the Y chromosome-encoded gene family involved in spermatogenesis. BPY2 is expressed predominantly in the testes and plays a crucial role in sperm development and maturation, particularly in the regulation of the protein synthesis and cellular processes necessary for normal sperm function. BPY2 inhibitors have been developed to study the molecular mechanisms through which BPY2 contributes to these processes, allowing researchers to gain insight into its precise biological functions and regulatory mechanisms.
BPY2 inhibitors are small molecules engineered to interact with critical regions of the BPY2 protein, such as its active or binding sites. By inhibiting BPY2's activity, these molecules can disrupt its interaction with other proteins or cellular structures involved in sperm development. The chemical makeup of BPY2 inhibitors often features moieties that enable selective binding to the BPY2 protein, ensuring targeted disruption without affecting other proteins in the cellular environment. This specificity allows scientists to investigate how the inhibition of BPY2 impacts sperm formation and maturation, leading to a deeper understanding of the molecular pathways regulated by BPY2. Through the use of these inhibitors, researchers can explore BPY2's role in male reproductive biology and its broader contribution to cellular processes related to protein regulation in spermatogenesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This compound is a DNA methyltransferase inhibitor that can cause hypomethylation of DNA, potentially reducing BPY2 expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A inhibits histone deacetylases, which could result in chromatin remodeling and decreased BPY2 expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
By binding to GC-rich DNA sequences, Mithramycin A inhibits transcription and could reduce BPY2 expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D intercalates into DNA, inhibiting transcription elongation and potentially reducing BPY2 expression. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol is a cyclin-dependent kinase inhibitor, which may lead to cell cycle arrest and downregulation of BPY2 expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Sirolimus inhibits mTOR, which could decrease protein synthesis globally, including that of BPY2. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat is a histone deacetylase inhibitor, which could disrupt chromatin structure leading to reduced BPY2 expression. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules and disrupts cell division, potentially affecting BPY2 expression in dividing cells. | ||||||
Bicalutamide | 90357-06-5 | sc-202976 sc-202976A | 100 mg 500 mg | $41.00 $143.00 | 27 | |
As an androgen receptor antagonist, Bicalutamide might indirectly affect BPY2 expression by altering hormonal balances. | ||||||
Ketoconazole | 65277-42-1 | sc-200496 sc-200496A | 50 mg 500 mg | $62.00 $260.00 | 21 | |
Ketoconazole inhibits steroid synthesis, potentially decreasing testosterone levels and indirectly lowering BPY2 expression. | ||||||