Date published: 2025-11-1

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BPY2 Inhibitors

BPY2 inhibitors are a class of chemical compounds designed to specifically target and inhibit the BPY2 (Basic Protein, Y-linked 2) protein, a member of the Y chromosome-encoded gene family involved in spermatogenesis. BPY2 is expressed predominantly in the testes and plays a crucial role in sperm development and maturation, particularly in the regulation of the protein synthesis and cellular processes necessary for normal sperm function. BPY2 inhibitors have been developed to study the molecular mechanisms through which BPY2 contributes to these processes, allowing researchers to gain insight into its precise biological functions and regulatory mechanisms.

BPY2 inhibitors are small molecules engineered to interact with critical regions of the BPY2 protein, such as its active or binding sites. By inhibiting BPY2's activity, these molecules can disrupt its interaction with other proteins or cellular structures involved in sperm development. The chemical makeup of BPY2 inhibitors often features moieties that enable selective binding to the BPY2 protein, ensuring targeted disruption without affecting other proteins in the cellular environment. This specificity allows scientists to investigate how the inhibition of BPY2 impacts sperm formation and maturation, leading to a deeper understanding of the molecular pathways regulated by BPY2. Through the use of these inhibitors, researchers can explore BPY2's role in male reproductive biology and its broader contribution to cellular processes related to protein regulation in spermatogenesis.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This compound is a DNA methyltransferase inhibitor that can cause hypomethylation of DNA, potentially reducing BPY2 expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Trichostatin A inhibits histone deacetylases, which could result in chromatin remodeling and decreased BPY2 expression.

Mithramycin A

18378-89-7sc-200909
1 mg
$54.00
6
(1)

By binding to GC-rich DNA sequences, Mithramycin A inhibits transcription and could reduce BPY2 expression.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D intercalates into DNA, inhibiting transcription elongation and potentially reducing BPY2 expression.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$254.00
41
(3)

Flavopiridol is a cyclin-dependent kinase inhibitor, which may lead to cell cycle arrest and downregulation of BPY2 expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Sirolimus inhibits mTOR, which could decrease protein synthesis globally, including that of BPY2.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Vorinostat is a histone deacetylase inhibitor, which could disrupt chromatin structure leading to reduced BPY2 expression.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$40.00
$73.00
$217.00
$242.00
$724.00
$1196.00
39
(2)

Paclitaxel stabilizes microtubules and disrupts cell division, potentially affecting BPY2 expression in dividing cells.

Bicalutamide

90357-06-5sc-202976
sc-202976A
100 mg
500 mg
$41.00
$143.00
27
(1)

As an androgen receptor antagonist, Bicalutamide might indirectly affect BPY2 expression by altering hormonal balances.

Ketoconazole

65277-42-1sc-200496
sc-200496A
50 mg
500 mg
$62.00
$260.00
21
(1)

Ketoconazole inhibits steroid synthesis, potentially decreasing testosterone levels and indirectly lowering BPY2 expression.