BPIL3 Inhibitors
BPIL3 Inhibitors are a class of chemical compounds that act by interfering with the biological processes and signaling pathways in which the BPIL3 protein is involved. This includes vital immune system processes such as the disruption of bacterial cell membranes. For instance, Lysozyme, an enzyme that lyses bacterial cell walls, can decrease the functional activity of BPIL3 by reducing the need for BPIL3 action due to already lysed bacterial cell walls. Similarly, D-Mannose, a sugar that blocks bacterial adhesion to human cells, can lead to decreased BPIL3 activity as the adhesion blockage reduces the number of bacteria available for BPIL3 to act upon.
Furthermore, compounds such as N-acetylcysteine, Gallic acid, Epigallocatechin gallate, Resveratrol, Curcumin, Quercetin, Catechin, Lactoferrin, and Capsaicin, which possess antimicrobial properties can reduce the bacterial load, thereby decreasing the functional activity of BPIL3. For example, N-acetylcysteine is a mucolytic agent that reduces bacterial load in the lungs, which can potentially decrease BPIL3 activity as there are fewer bacteria for it to act upon. Similarly, Gallic acid and Epigallocatechin gallate are antioxidants that inhibit bacterial growth, which could lead to decreased activity of BPIL3. Another compound, Sphingosine-1-phosphate, a sphingolipid that modulates immune response, couldindirectly inhibit BPIL3 via its immune modulatory effects. All these compounds contribute to the indirect inhibition of BPIL3 by acting on the bacterial population or the immune response, which are key factors in the functional activity of BPIL3.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
Sphingosine-1-phosphate (S1P) is a sphingolipid that can modulate immune response by acting on S1P receptors. BPIL3, being part of the immune system's response to bacterial infection, could be indirectly inhibited by S1P's immune modulatory effects, leading to decreased BPIL3 activity. | ||||||
D-Mannose | 3458-28-4 | sc-211180 sc-211180A | 100 g 250 g | $101.00 $158.00 | 1 | |
D-Mannose is a sugar that binds to certain bacteria, blocking their adhesion to human cells. As BPIL3 acts on bacteria by disrupting their cell membranes, the adhesion blockage by D-Mannose could lead to decreased BPIL3 activity. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
N-acetylcysteine acts as a mucolytic agent, breaking down mucus in the lungs. It can reduce the bacterial load, potentially decreasing BPIL3 activity as there are fewer bacteria for it to act upon. | ||||||
Gallic acid | 149-91-7 | sc-205704 sc-205704A sc-205704B | 10 g 100 g 500 g | $55.00 $85.00 $240.00 | 14 | |
Gallic acid is an organic acid with antioxidant properties. It inhibits bacterial growth, which could lead to decreased activity of BPIL3, whose function is to disrupt bacterial cell membranes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin gallate is a potent antioxidant and has antimicrobial properties. Its antimicrobial activity could reduce the bacterial load, thereby decreasing the functional activity of BPIL3. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol has antioxidative and antimicrobial properties. By reducing the bacterial load, it could decrease the functional activity of BPIL3. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has antimicrobial properties that could reduce the bacterial load, leading to decreased activity of BPIL3. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin has both antioxidant and antimicrobial properties. Its antimicrobial activity could reduce the bacterial load, thereby decreasing the functional activity of BPIL3. | ||||||
Catechin | 154-23-4 | sc-205624 sc-205624A | 1 mg 5 mg | $130.00 $293.00 | 3 | |
Catechin is a type of natural phenol and antioxidant. It also possesses antimicrobial properties, which could decrease the functional activity of BPIL3 by reducing the bacterial load. | ||||||
Lactoferrin | 146897-68-9 | sc-394420 sc-394420A sc-394420B sc-394420C | 10 mg 50 mg 100 mg 1 g | $120.00 $400.00 $569.00 $1465.00 | ||
Lactoferrin is an iron-binding protein with bacteriostatic properties due to its ability to sequester iron. This could decrease the functional activity of BPIL3, as there would be fewer bacteria for it to act upon. | ||||||