Date published: 2026-4-1

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BPAG1n3 Inhibitors

BPAG1n3 inhibitors, also known as BPAG1n3 (BPAG1-nerve-specific 3 isoform) protein inhibitors, represent a class of chemical compounds designed to selectively target and modulate the activity of the BPAG1n3 protein. BPAG1n3 is a specific isoform of the BPAG1 (Bullous Pemphigoid Antigen 1) protein family, which plays a crucial role in maintaining the structural integrity of skin and nerve cells. These inhibitors are engineered to interfere with the function of BPAG1n3, thereby offering potential insights into the molecular mechanisms governing skin and neuronal biology.

The BPAG1n3 protein, primarily expressed in nerve cells, contributes to the stability and integrity of the axonal cytoskeleton by linking it to the extracellular matrix. BPAG1n3 inhibitors are designed to target specific regions or molecular interactions associated with this protein, aiming to disrupt its function or interactions with other cellular components. By selectively modulating BPAG1n3, researchers can investigate its role in various cellular processes, such as axonal transport, neuronal development, and synaptic plasticity. This class of inhibitors serves as valuable research tools for probing the intricate pathways and interactions that underlie the maintenance of neural structures and the functioning of the skin. It is important to note that the primary utility of BPAG1n3 inhibitors lies in advancing our fundamental understanding of cell biology and may have potential implications in various fields, although their specific applications in therapy or medicine are not within the scope of this description.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Imatinib

152459-95-5sc-267106
sc-267106A
sc-267106B
10 mg
100 mg
1 g
$26.00
$119.00
$213.00
27
(1)

Inhibits the tyrosine kinase activity of Bcr-Abl, blocking its signaling cascade, which is essential for the growth and survival of cancer cells.

Gefitinib

184475-35-2sc-202166
sc-202166A
sc-202166B
sc-202166C
100 mg
250 mg
1 g
5 g
$63.00
$114.00
$218.00
$349.00
74
(2)

Targets the epidermal growth factor receptor (EGFR), blocking the activation of downstream signaling pathways involved in cell proliferation.

Erlotinib, Free Base

183321-74-6sc-396113
sc-396113A
sc-396113B
sc-396113C
sc-396113D
500 mg
1 g
5 g
10 g
100 g
$87.00
$135.00
$293.00
$505.00
$3827.00
42
(0)

Also inhibits EGFR, hindering the phosphorylation of tyrosine residues and the subsequent cell division and growth.

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$57.00
$100.00
$250.00
129
(3)

Multi-kinase inhibitor that disrupts the Raf/MEK/ERK pathway and VEGFR/PDGFR signaling, reducing angiogenesis and tumor cell proliferation.

Sunitinib Malate

341031-54-7sc-220177
sc-220177A
sc-220177B
10 mg
100 mg
3 g
$197.00
$520.00
$1093.00
4
(1)

Targets multiple receptor tyrosine kinases (RTKs) like VEGFR, PDGFR, and c-KIT, impeding tumor angiogenesis and cell survival.

Lapatinib

231277-92-2sc-353658
100 mg
$420.00
32
(1)

Dual EGFR/HER2 inhibitor, blocking both receptors' kinase activities, which are often overexpressed in cancer cells.

MDV3100

915087-33-1sc-364354
sc-364354A
5 mg
50 mg
$245.00
$1051.00
7
(1)

Acts as an androgen receptor (AR) antagonist, preventing AR translocation to the nucleus and inhibiting AR-mediated gene transcription in prostate cancer.

Everolimus

159351-69-6sc-218452
sc-218452A
5 mg
50 mg
$131.00
$651.00
7
(1)

mTOR inhibitor that interferes with the PI3K/Akt/mTOR pathway, impeding cell growth and proliferation.

Olaparib

763113-22-0sc-302017
sc-302017A
sc-302017B
250 mg
500 mg
1 g
$210.00
$305.00
$495.00
10
(1)

PARP inhibitor, disrupting DNA repair mechanisms in BRCA-mutated cancer cells, leading to genomic instability and cell death.

Abiraterone

154229-19-3sc-460288
10 mg
$276.00
(0)

Inhibits CYP17A1, an enzyme crucial for androgen biosynthesis, lowering androgen levels in prostate cancer.