Date published: 2025-10-14

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BID Inhibitors

BID inhibitors are a class of chemical compounds designed to selectively target and inhibit the function of the BH3-interacting domain death agonist (BID) protein. BID is a key member of the Bcl-2 family of proteins, which play a crucial role in regulating apoptosis, a highly regulated and tightly controlled process of programmed cell death. BID itself acts as a mediator between the extrinsic and intrinsic pathways of apoptosis, where it can be activated by specific apoptotic signals. By inhibiting BID, these compounds aim to interfere with its pro-apoptotic functions and disrupt its role in initiating the apoptotic cascade. BID is known to play a critical role in transmitting apoptotic signals from death receptors on the cell surface to the mitochondria, ultimately leading to the release of apoptogenic factors and activation of downstream apoptotic pathways. BID inhibitors could modulate the delicate balance between cell survival and death by interfering with these crucial apoptotic pathways. Studying the effects of BID inhibitors can provide insights into the intricate regulatory mechanisms of apoptosis and help further our understanding of the molecular events that govern cell fate decisions.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

BI-6C9

791835-21-7sc-210915
sc-210915A
1 mg
5 mg
$67.00
$296.00
3
(1)

Acts as an inhibitor of BID, a protein involved in apoptosis regulation. It may interfere with BID's function, affecting its role in cellular processes.

Emricasan

254750-02-2sc-507387
5 mg
$90.00
(0)

Emricasan is a potential BID inhibitor that might impact apoptosis pathways by inhibiting caspases, potentially preventing BID cleavage and activation.

YM 155

781661-94-7sc-364661
sc-364661A
5 mg
25 mg
$129.00
$497.00
3
(0)

YM-155 is a small molecule that might inhibit BID expression through transcriptional regulation, potentially affecting apoptosis signaling.

Sabutoclax

1228108-65-3sc-472977
1 mg
$330.00
(0)

Sabutoclax is a BH3 mimetic that might inhibit BID by binding to Bcl-2 family proteins, preventing apoptosis induction.

Obatoclax Mesylate

803712-79-0sc-364221
sc-364221A
5 mg
10 mg
$94.00
$138.00
(1)

Obatoclax Mesylate is a potential BID inhibitor that might interfere with anti-apoptotic proteins, promoting apoptosis in cancer cells.

HA14-1

65673-63-4sc-205911
sc-205911A
5 mg
25 mg
$58.00
$205.00
(1)

HA14-1 is a small molecule that could inhibit BID by targeting Bcl-2 family members, potentially inducing apoptosis.

TW-37

877877-35-5sc-361387
sc-361387A
10 mg
50 mg
$200.00
$860.00
2
(1)

TW-37 is a potential BID inhibitor that might interfere with Bcl-2 family proteins, inducing apoptosis in cancer cells.

Gossypol

303-45-7sc-200501
sc-200501A
25 mg
100 mg
$114.00
$225.00
12
(1)

Gossypol is a natural compound that might inhibit BID by targeting Bcl-2 family members, promoting apoptosis.

ABT 737

852808-04-9sc-207242
2.5 mg
$200.00
54
(3)

ABT-737 is a BH3 mimetic that might inhibit BID by disrupting Bcl-2 family interactions, inducing apoptosis in cancer cells.

A-1210477

1668553-26-1sc-507474
5 mg
$195.00
(0)

A-1210477 is a potential BID inhibitor that might target Bcl-2 family members, promoting apoptosis in cancer cells.