BChE Activators
BChE activators encompass a diverse range of chemicals that either directly or indirectly modulate the activity of butyrylcholinesterase (BChE), an enzyme involved in cholinergic neurotransmission. Clioquinol, an ionophore, indirectly activates BChE by influencing metal ion homeostasis, particularly zinc and copper. Memantine, an NMDA receptor antagonist, indirectly activates BChE by modulating glutamatergic signaling, enhancing BChE activity. Gallic Acid, a natural polyphenol, indirectly activates BChE by exerting antioxidant effects. Sodium Orthovanadate, a protein tyrosine phosphatase inhibitor, indirectly activates BChE by affecting intracellular signaling, leading to increased BChE activity. Dihydrolipoic Acid, a powerful antioxidant, indirectly activates BChE by influencing redox signaling, and Quercetin, a flavonoid, similarly activates BChE through antioxidant effects.
α-Lipoic Acid, a coenzyme with antioxidant properties, and Carnosic Acid, a natural antioxidant, both indirectly activate BChE by modulating oxidative stress-related pathways. Piceatannol, a natural stilbene, indirectly activates BChE by modulating intracellular signaling, including antioxidant effects. Huperzine A, an acetylcholinesterase inhibitor, indirectly activates BChE by influencing cholinergic signaling through increased acetylcholine levels. Epicatechin, a natural flavonoid, and Naringenin, a citrus flavonoid, both indirectly activate BChE by exerting antioxidant effects. These chemicals collectively highlight the diverse mechanisms through which BChE activation can be achieved, providing more insight into cholinergic neurotransmission. Further research into the specific pathways and molecular interactions underlying these effects is essential for a comprehensive understanding of BChE regulation and its implications in various biological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Clioquinol | 130-26-7 | sc-201066 sc-201066A | 1 g 5 g | $44.00 $113.00 | 2 | |
Clioquinol, an ionophore, indirectly activates BChE by influencing metal ion homeostasis. Acting as a zinc and copper ion chelator, Clioquinol alters metal-dependent pathways that modulate BChE activity. | ||||||
Memantine hydrochloride | 41100-52-1 | sc-203628 | 50 mg | $68.00 | 4 | |
Memantine, an NMDA receptor antagonist, indirectly activates BChE by modulating glutamatergic signaling. By binding to NMDA receptors, Memantine influences downstream signaling cascades, potentially enhancing BChE activity. | ||||||
Gallic acid | 149-91-7 | sc-205704 sc-205704A sc-205704B | 10 g 100 g 500 g | $55.00 $85.00 $240.00 | 14 | |
Gallic Acid, a natural polyphenol, indirectly activates BChE by exerting antioxidant effects. Through its antioxidant properties, Gallic Acid may modulate signaling pathways related to oxidative stress, leading to enhanced BChE activity. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $45.00 $56.00 $183.00 | 142 | |
Sodium Orthovanadate, a protein tyrosine phosphatase inhibitor, indirectly activates BChE by affecting intracellular signaling. By inhibiting phosphatases, Sodium Orthovanadate modulates signaling pathways that may lead to increased BChE activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid, indirectly activates BChE by exerting antioxidant effects. Through its antioxidant properties, Quercetin may modulate signaling pathways related to oxidative stress, leading to enhanced BChE activity. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
α-Lipoic Acid, a coenzyme with antioxidant properties, indirectly activates BChE by influencing redox signaling. Through its antioxidant effects, α-Lipoic Acid may modulate pathways related to oxidative stress, leading to enhanced BChE activity. | ||||||
Carnosic acid | 3650-09-7 | sc-202520 sc-202520A | 10 mg 50 mg | $60.00 $165.00 | 6 | |
Carnosic Acid, a natural antioxidant, indirectly activates BChE by exerting antioxidant effects. Through its antioxidant properties, Carnosic Acid may modulate signaling pathways related to oxidative stress, leading to enhanced BChE activity. | ||||||
Piceatannol | 10083-24-6 | sc-200610 sc-200610A sc-200610B | 1 mg 5 mg 25 mg | $50.00 $70.00 $195.00 | 11 | |
Piceatannol, a natural stilbene, indirectly activates BChE by modulating intracellular signaling. Through its various cellular effects, including antioxidant properties, Piceatannol may influence pathways leading to increased BChE activity. | ||||||
(−)-Huperzine A | 102518-79-6 | sc-200183 sc-200183A | 1 mg 5 mg | $140.00 $355.00 | 1 | |
Huperzine A, an acetylcholinesterase inhibitor, indirectly activates BChE by influencing cholinergic signaling. By inhibiting acetylcholinesterase, Huperzine A increases acetylcholine levels, leading to competitive activation of BChE. | ||||||
(−)Epicatechin | 490-46-0 | sc-205672 sc-205672A | 1 mg 5 mg | $50.00 $135.00 | ||
Epicatechin, a natural flavonoid, indirectly activates BChE by exerting antioxidant effects. Through its antioxidant properties, Epicatechin may modulate signaling pathways related to oxidative stress, leading to enhanced BChE activity. | ||||||