BC052486 Inhibitors
BC052486, a protein of significant interest in cellular biology, plays a pivotal role in the modulation of transcriptional regulation and cellular processes related to cell growth and differentiation. While its specific functions are still under exploration, it is evident that BC052486 is intricately connected to various signaling pathways that govern key aspects of cellular physiology. Understanding the intricate network of interactions involving BC052486 is crucial for deciphering its functional significance in cellular contexts. BC052486 inhibition is achieved through a series of compounds targeting key signaling pathways and cellular processes associated with BC052486 function. These inhibitors impact BC052486 expression and activity indirectly by modulating pathways such as TGF-β, PI3K/Akt, MAPK/ERK, JNK, Wnt/β-catenin, p38 MAPK, Rho/ROCK, and mTOR. For instance, compounds like SB-431542 disrupt TGF-β signaling, influencing BC052486 by altering downstream cellular responses linked to transcriptional regulation. Similarly, LY294002 and Wortmannin target the PI3K/Akt pathway, affecting BC052486 expression and function in the context of cellular growth and differentiation. The intricate interplay between these pathways and BC052486 provides a foundation for understanding the complex regulatory mechanisms governing cellular processes.
Among the inhibitors listed, GSK-3 Inhibitor IX and LY2090314 specifically target the Wnt/β-catenin pathway, influencing BC052486 indirectly through GSK-3 inhibition. These compounds highlight the interconnectedness of BC052486 with Wnt signaling and the potential impact on cellular processes related to cell growth and differentiation. Additionally, the BET bromodomain inhibitor JQ1 and the mTOR inhibitor AZD8055 offer insights into the role of chromatin accessibility and the mTOR pathway in BC052486-mediated transcriptional regulation. In summary, BC052486 inhibitors provide valuable tools for unraveling the functional significance of this protein in cellular processes. The diverse mechanisms of inhibition, targeting multiple signaling pathways, offer a nuanced perspective on the interconnected regulatory networks that converge on BC052486. Continued research into the precise functions of BC052486 and the effects of these inhibitors will undoubtedly contribute to a deeper understanding of the intricate molecular pathways governing cellular growth and differentiation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
TGF-β receptor inhibitor. SB-431542 prevents the activation of TGF-β signaling, indirectly influencing BC052486 by disrupting the TGF-β pathway. This interference alters downstream cellular responses governed by BC052486, impacting transcriptional regulation and cellular processes related to cell growth and differentiation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor targeting the PI3K/Akt pathway. LY294002 disrupts the PI3K/Akt pathway, which crosstalks with BC052486 signaling. This disruption influences BC052486 expression and function, altering downstream cellular processes associated with transcriptional regulation and cellular differentiation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor. SP600125 affects the JNK pathway, which can modulate BC052486 expression and function in specific cellular contexts. By blocking JNK activity, this inhibitor indirectly influences BC052486-mediated cellular processes related to transcriptional regulation and cell growth. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
GSK-3 inhibitor affecting the Wnt/β-catenin pathway. By inhibiting GSK-3, this compound influences BC052486 indirectly, as GSK-3 participates in the regulation of the Wnt/β-catenin pathway, which crosstalks with BC052486 signaling. The modulation of this pathway alters BC052486 expression and function, impacting transcriptional regulation and cellular processes related to cell growth and differentiation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAPK inhibitor. SB-203580 affects the p38 MAPK pathway, which can modulate BC052486 expression and function in specific cellular contexts. By blocking p38 MAPK activity, this inhibitor indirectly influences BC052486-mediated cellular processes related to transcriptional regulation and cell growth. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Irreversible PI3K inhibitor. Inhibiting PI3K disrupts the PI3K/Akt pathway, which crosstalks with BC052486 signaling. This disruption influences BC052486 expression and function, altering downstream cellular processes associated with transcriptional regulation and cellular differentiation. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor. Y-27632 affects the Rho/ROCK pathway, which can modulate BC052486 expression and function in specific cellular contexts. By inhibiting ROCK activity, this compound indirectly influences BC052486-mediated cellular processes related to transcriptional regulation and cell growth. | ||||||
LY2090314 | 603288-22-8 | sc-507359 | 5 mg | $175.00 | ||
GSK-3 inhibitor targeting the Wnt/β-catenin pathway. LY2090314 influences BC052486 indirectly by inhibiting GSK-3, a key regulator of the Wnt/β-catenin pathway that intersects with BC052486 signaling. This interference alters BC052486 expression and function, impacting transcriptional regulation and cellular processes related to cell growth and differentiation. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
BET bromodomain inhibitor. (+/-)-JQ1 influences BC052486 expression by targeting BET proteins, including BRD4. This inhibitor affects chromatin accessibility and gene expression, indirectly modulating BC052486-mediated transcriptional regulation and cellular processes related to cell growth and differentiation. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $163.00 $352.00 | 12 | |
mTOR inhibitor. AZD8055 disrupts the mTOR pathway, which crosstalks with BC052486 signaling. This interference influences BC052486 expression and function, impacting transcriptional regulation and cellular processes related to cell growth and differentiation. | ||||||