Chemical inhibitors of BC026682 exhibit a range of actions on signaling pathways that ultimately lead to its functional inhibition. Staurosporine serves as a broad-spectrum protein kinase inhibitor, which can inhibit kinase-dependent functions of proteins like BC026682, thereby disrupting their activity. Similarly, both wortmannin and LY294002 act as inhibitors of PI3K, a kinase that participates in pivotal signaling cascades. The inhibition of PI3K by these compounds can lead to the cessation of downstream signaling processes that are essential for the functional activity of BC026682.
Rapamycin, targeting mTOR kinase, can impede the mTOR signaling pathway, which often regulates proteins akin to BC026682, leading to their functional inhibition. PD98059 and U0126 both target MEK, a key kinase within the MAPK/ERK pathway. The inhibition of MEK by these compounds can prevent the activation of ERK, which may be required for BC026682 activity. SB203580 and SP600125 inhibit p38 MAP kinase and JNK, respectively, leading to an interruption in signaling pathways that could contribute to BC026682's regulation and function. Triciribine specifically inhibits AKT, a serine/threonine-specific protein kinase that is involved in various signaling pathways, and its inhibition can disrupt processes that would otherwise lead to the activation of BC026682.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Inhibits a broad range of protein kinases that could be upstream of BC026682, potentially leading to the inhibition of this protein's kinase-dependent functions. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K, which is involved in multiple signaling pathways that could include the activation of BC026682, leading to its functional inhibition. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR, a kinase that can regulate proteins like BC026682 through complex signaling networks. By inhibiting mTOR, proteins downstream or associated with the mTOR pathway, including BC026682, can be functionally inhibited. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, which is involved in the MAPK/ERK pathway that may regulate proteins like BC026682. Inhibition of MEK can lead to the functional inhibition of downstream proteins, including BC026682. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Inhibits MEK, and consequently inhibits the ERK pathway, potentially leading to the inhibition of proteins that are regulated by this pathway, such as BC026682. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAP kinase, which may play a role in pathways that regulate the function of BC026682. Inhibition of p38 MAP kinase can thus inhibit the function of BC026682. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $65.00 $267.00 | 257 | |
Inhibits JNK, and through this action, it can inhibit cellular processes that involve proteins regulated by JNK, including BC026682. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, potentially leading to the functional inhibition of proteins like BC026682 that are downstream of PI3K signaling. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Inhibits AKT, which is involved in signaling pathways that could regulate BC026682. Inhibition of AKT can lead to the functional inhibition of BC026682. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
Inhibits EGFR tyrosine kinase, which may be involved in signaling pathways that regulate BC026682. Inhibition of EGFR can lead to the functional inhibition of BC026682. |