BACE Activators
BACE activators belong to a specific class of chemical compounds designed to modulate the activity of Beta-Secretase (BACE), also known as Beta-Site Amyloid Precursor Protein Cleaving Enzyme. BACE is an enzyme central to the amyloidogenic pathway, which is associated with the processing of amyloid precursor protein (APP). This pathway is particularly noteworthy in the context of Alzheimer's disease research, as it leads to the generation of amyloid beta (Aβ) peptides, which are known to accumulate in the brains of individuals with Alzheimer's disease. BACE cleaves APP, initiating the production of Aβ peptides that can subsequently aggregate and form the amyloid plaques characteristic of Alzheimer's pathology.
BACE activators are meticulously designed compounds that interact with the BACE enzyme, affecting its catalytic activity. These activators play a critical role in the field of Alzheimer's disease research, as they provide a means to explore the molecular mechanisms underlying Aβ peptide production. By manipulating BACE activity, scientists can gain insights into the intricate processes governing Aβ generation and its links to Alzheimer's disease pathogenesis. BACE activators are instrumental in advancing our understanding of the fundamental aspects of Alzheimer's disease biology, contributing to the broader field of neuroscience and molecular biology.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a natural phenol found in grapes, may upregulate BACE expression through pathways related to cellular stress responses. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a compound in turmeric, may influence BACE expression by modulating pathways associated with inflammation and oxidative stress. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine, a central nervous system stimulant, may alter BACE expression by affecting neuronal activity and cellular metabolism. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride, often used in psychiatric treatments, might impact BACE expression through its effects on glycogen synthase kinase-3 (GSK-3) pathways. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, a metabolite of vitamin A, can potentially modulate BACE expression through retinoid signaling pathways involved in neurodevelopment. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
DL-Sulforaphane, found in cruciferous vegetables, might upregulate BACE expression by activating pathways related to cellular detoxification. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid found in many fruits and vegetables, could affect BACE expression through its antioxidant and anti-inflammatory properties. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Cholecalciferol, a fat-soluble vitamin, can potentially alter BACE expression through its roles in immune regulation and brain health. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Green tea extract, rich in catechins, may impact BACE expression by modulating pathways associated with neuroprotection and metabolism. | ||||||