ATP11 Activators
Chemical activators of ATP11 are compounds that influence mitochondrial biogenesis, function, or membrane composition, thereby indirectly affecting ATP11. These activators function by modulating signaling pathways and cellular states that are conducive to the enhancement of mitochondrial content and activity. For instance, bezafibrate and pioglitazone are PPAR agonists that stimulate the biogenesis of mitochondria, which may lead to a greater need for ATP11's role in assembling and maintaining mitochondrial membranes. Leucine, through mTOR activation, and AICAR, via AMPK activation, promote mitochondrial biogenesis, which could increase the expression and function of mitochondrial proteins, including ATP11.
Furthermore, mitochondrial-targeted compounds like coenzyme Q10 and alpha-lipoic acid are essential for optimal mitochondrial function and may increase the requirement for ATP11 to maintain mitochondrial integrity. Compounds such as urolithin A and PQQ enhance mitophagy and mitochondrial biogenesis, respectively, and may create conditions that necessitate increased activity of ATP11. Sirtuin activators like SRT1720 and resveratrol also support mitochondrial biogenesis, influencing ATP11 indirectly. Lastly, curcumin and NAD+ precursors support mitochondrial function and can impact ATP11 activity necessary for the assembly and maintenance of mitochondrial phospholipid composition.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
Activates PPARs, which can promote mitochondrial biogenesis, potentially increasing the demand for ATP11 activity in mitochondrial membrane remodeling. | ||||||
L-Leucine | 61-90-5 | sc-364173 sc-364173A | 25 g 100 g | $21.00 $61.00 | ||
Activates mTOR signaling, which can enhance mitochondrial biogenesis and may indirectly upregulate ATP11 as part of the increased mitochondrial content. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
Activates AMPK, which can promote mitochondrial biogenesis and possibly the function of mitochondrial proteins including ATP11. | ||||||
Urolithin A | 1143-70-0 | sc-475514 sc-475514A sc-475514B sc-475514C | 25 mg 100 mg 1 g 5 g | $200.00 $450.00 $700.00 $1200.00 | 10 | |
Induces mitophagy and mitochondrial biogenesis, potentially increasing the requirement for ATP11 in new mitochondria. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
Precursor for NAD, which is vital for mitochondrial function, potentially upregulating ATP11 to support increased mitochondrial activity. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
PPARγ agonist that promotes mitochondrial biogenesis, possibly enhancing ATP11 function in new mitochondria. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Essential for mitochondrial electron transport chain, which may indirectly necessitate increased ATP11 activity for optimal mitochondrial function. | ||||||
SRT1720 | 1001645-58-4 | sc-364624 sc-364624A | 5 mg 10 mg | $193.00 $357.00 | 13 | |
SIRT1 activator, which can enhance mitochondrial biogenesis, potentially leading to an increased role for ATP11 in mitochondrial membrane assembly. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates mitochondrial biogenesis and function, which may require enhanced ATP11 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Activates SIRT1, promoting mitochondrial biogenesis and potentially ATP11 activity as part of enhanced mitochondrial function. | ||||||