ASPH Activators
The chemical class of ASPH Activators encompasses a diverse group of compounds that indirectly influence the activity of ASPH through various biochemical or cellular mechanisms. These chemicals primarily act by modulating gene expression, cell signaling pathways, and chromatin structure, all of which are crucial to ASPH's function. Histone deacetylase inhibitors like Sodium Butyrate and Trichostatin A alter chromatin structure and gene expression, potentially impacting pathways involving ASPH, particularly in cellular differentiation and migration. Similarly, PI3K and mTOR inhibitors (LY294002, Rapamycin) affect pathways related to cell growth and proliferation, thereby having an indirect influence on ASPH's activity in these processes.
Moreover, compounds such as MEK inhibitors (PD98059, U0126) and MAPK pathway inhibitors (SB203580, SP600125) modulate cell signaling pathways that are crucial for cell proliferation, differentiation, and stress responses. These pathways are relevant to the role of ASPH in cellular functions. DNA methyltransferase inhibitors like 5-Azacytidine can also alter gene expression patterns, potentially affecting ASPH activity in cell differentiation processes. ROCK inhibitors (Y-27632) and sirtuin inhibitors (Nicotinamide) further contribute to this class by influencing cell morphology, motility, aging, and differentiation, thereby potentially impacting the functional role of ASPH in these cellular contexts.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A histone deacetylase inhibitor. It can influence gene expression patterns, potentially affecting ASPH activity by altering the expression of genes involved in cell proliferation and migration pathways. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Another histone deacetylase inhibitor. By altering chromatin structure and gene expression, it may impact pathways where ASPH plays a role, particularly in cellular differentiation and migration. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor. It affects the PI3K/Akt pathway, which is involved in various cellular processes including those related to ASPH activity, such as cell migration and proliferation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor. It can influence cell growth and proliferation pathways, potentially affecting ASPH's role in these processes. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An MEK inhibitor. It may indirectly influence ASPH activity by affecting the MAPK/ERK pathway, which is involved in cell proliferation and differentiation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor. By influencing the p38 MAPK pathway, it can indirectly affect ASPH-related cellular processes, especially in stress response and inflammation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
An inhibitor of DNA methyltransferases. It can alter gene expression and is known to affect pathways involved in cell differentiation, potentially impacting ASPH activity. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor. It influences cell morphology and motility, pathways where ASPH might play a role, especially in the context of cell migration. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor. By modulating the JNK pathway, it can impact cellular processes relevant to ASPH, such as apoptosis and cell differentiation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A PI3K/Akt pathway inhibitor. This compound can influence various cellular processes, potentially affecting ASPH activity in pathways related to cell growth and survival. | ||||||