ARMCX3 Activators
ARMCX3 Activators represent a diverse class of compounds that can indirectly influence the activity of ARMCX3 through various cellular mechanisms and signaling pathways. Forskolin, through its elevation of cAMP, activates PKA, which can phosphorylate a myriad of proteins within the cell, including or affecting those that interact with ARMCX3. This could lead to a functional enhancement of ARMCX3 by a post-translational modification such as phosphorylation, which often changes the activity or localization of proteins. Similarly, PMA's activation of PKC could lead to the phosphorylation of proteins that interact with ARMCX3, thereby influencing its activity. PKC is known to phosphorylate a wide range of target proteins, which can have diverse effects on cellular functions, including protein-protein interactions that could affect ARMCX3.
The activation of PKC by PMA and the modulation of calcium-dependent pathways by ionomycin provide mechanisms by which ARMCX3 could be enhanced through phosphorylation and calcium-mediated signaling. The nitric oxide donor SNAP, by increasing cGMP levels, indirectly affects ARMCX3 through cGMP-dependent kinases.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin directly stimulates adenylyl cyclase, leading to an increase in cyclic AMP (cAMP) levels, which in turn activates PKA. PKA can phosphorylate various proteins and could enhance ARMCX3 activity by phosphorylation-dependent mechanisms. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which is involved in numerous signaling pathways. PKC activation can lead to phosphorylation of proteins that may interact with or regulate ARMCX3, thus enhancing its activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that raises intracellular calcium levels, activating calcium-dependent proteins and pathways that could lead to the enhancement of ARMCX3 activity through calcium-dependent signaling. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin binds to its receptor and activates the PI3K/Akt signaling pathway, which plays a role in the regulation of various cellular processes. Akt can phosphorylate substrates that may modulate ARMCX3 activity. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Estrogen binds to estrogen receptors, which can activate signaling pathways such as the MAPK pathway, potentially leading to enhancement of ARMCX3 activity via downstream effects. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone interacts with glucocorticoid receptors, which can modulate inflammatory response pathways. This modulation could lead to an indirect enhancement of ARMCX3 activity by altering the cellular environment. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride inhibits GSK-3, a kinase involved in Wnt signaling. Inhibition of GSK-3 could stabilize proteins in the Wnt pathway, indirectly influencing ARMCX3 activity by stabilizing interacting proteins or upstream activators. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid binds to retinoic acid receptors, which can affect gene expression. This could indirectly enhance ARMCX3 activity through transcriptional regulation of interacting proteins or signaling molecules. | ||||||
(±)-S-Nitroso-N-acetylpenicillamine | 79032-48-7 | sc-200319B sc-200319 sc-200319A | 10 mg 20 mg 100 mg | $73.00 $112.00 $367.00 | 18 | |
Nitric oxide donors release nitric oxide, which can activate guanylyl cyclase, increasing cGMP levels. Elevated cGMP could enhance ARMCX3 activity indirectly through cGMP-dependent protein kinases or signaling cascades. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
H2O2 is a reactive oxygen species that can activate redox-sensitive signaling pathways. These pathways may influence ARMCX3 activity by affecting the oxidative state of interacting proteins or secondary messengers. | ||||||