The chemical class of ARID1B Activators includes a range of compounds that can potentially stimulate or modulate the expression and activity of ARID1B, mainly through their effects on gene expression regulation and chromatin remodeling. This class encompasses DNA methyltransferase inhibitors like 5-Azacytidine and HDAC inhibitors such as Trichostatin A, Valproic Acid, Vorinostat, and Sodium Butyrate, which can alter chromatin structure and enhance gene expression, potentially affecting ARID1B.
Lithium Chloride, with its broad impact on cellular signaling pathways, and agents like Retinoic Acid and Beta-Estradiol, which influence cell differentiation and gene expression, might also affect ARID1B. Forskolin, known to increase cAMP levels, can modulate various signaling pathways, potentially enhancing ARID1B expression. An mTOR inhibitor like Rapamycin and natural compounds such as Curcumin and EGCG, with their respective roles in cell growth regulation and antioxidant properties, are also considered for their potential to influence ARID1B.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can lead to demethylation of DNA, potentially influencing the expression of genes including ARID1B. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor, it can alter chromatin structure and enhance gene expression, potentially including ARID1B. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Another HDAC inhibitor that can affect gene expression, potentially upregulating ARID1B. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
An HDAC inhibitor known to impact chromatin remodeling and gene expression, potentially influencing ARID1B expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Can modulate several signaling pathways, potentially influencing ARID1B expression and activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Involved in cell differentiation and gene expression, retinoic acid might influence ARID1B expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As an HDAC inhibitor, it might influence ARID1B expression by altering chromatin accessibility. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
As a hormone that influences gene expression, beta-estradiol might indirectly affect ARID1B expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases cAMP levels, which can modulate various signaling pathways and potentially enhance ARID1B expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Known for its anti-inflammatory effects, curcumin can modulate various signaling pathways, potentially leading to the activation of ARID1B. |