Date published: 2025-10-22

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ARID1B Activators

The chemical class of ARID1B Activators includes a range of compounds that can potentially stimulate or modulate the expression and activity of ARID1B, mainly through their effects on gene expression regulation and chromatin remodeling. This class encompasses DNA methyltransferase inhibitors like 5-Azacytidine and HDAC inhibitors such as Trichostatin A, Valproic Acid, Vorinostat, and Sodium Butyrate, which can alter chromatin structure and enhance gene expression, potentially affecting ARID1B.

Lithium Chloride, with its broad impact on cellular signaling pathways, and agents like Retinoic Acid and Beta-Estradiol, which influence cell differentiation and gene expression, might also affect ARID1B. Forskolin, known to increase cAMP levels, can modulate various signaling pathways, potentially enhancing ARID1B expression. An mTOR inhibitor like Rapamycin and natural compounds such as Curcumin and EGCG, with their respective roles in cell growth regulation and antioxidant properties, are also considered for their potential to influence ARID1B.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A DNA methyltransferase inhibitor that can lead to demethylation of DNA, potentially influencing the expression of genes including ARID1B.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

An HDAC inhibitor, it can alter chromatin structure and enhance gene expression, potentially including ARID1B.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Another HDAC inhibitor that can affect gene expression, potentially upregulating ARID1B.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

An HDAC inhibitor known to impact chromatin remodeling and gene expression, potentially influencing ARID1B expression.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Can modulate several signaling pathways, potentially influencing ARID1B expression and activity.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Involved in cell differentiation and gene expression, retinoic acid might influence ARID1B expression.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

As an HDAC inhibitor, it might influence ARID1B expression by altering chromatin accessibility.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$62.00
$178.00
8
(1)

As a hormone that influences gene expression, beta-estradiol might indirectly affect ARID1B expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Increases cAMP levels, which can modulate various signaling pathways and potentially enhance ARID1B expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Known for its anti-inflammatory effects, curcumin can modulate various signaling pathways, potentially leading to the activation of ARID1B.