ARID1B Activators

The chemical class of ARID1B Activators includes a range of compounds that can potentially stimulate or modulate the expression and activity of ARID1B, mainly through their effects on gene expression regulation and chromatin remodeling. This class encompasses DNA methyltransferase inhibitors like 5-Azacytidine and HDAC inhibitors such as Trichostatin A, Valproic Acid, Vorinostat, and Sodium Butyrate, which can alter chromatin structure and enhance gene expression, potentially affecting ARID1B.

Lithium Chloride, with its broad impact on cellular signaling pathways, and agents like Retinoic Acid and Beta-Estradiol, which influence cell differentiation and gene expression, might also affect ARID1B. Forskolin, known to increase cAMP levels, can modulate various signaling pathways, potentially enhancing ARID1B expression. An mTOR inhibitor like Rapamycin and natural compounds such as Curcumin and EGCG, with their respective roles in cell growth regulation and antioxidant properties, are also considered for their potential to influence ARID1B.