ARGFX activators refer to a class of compounds designed to enhance the activity of the ARGFX protein, a homeobox gene that is part of the larger family of homeodomain-containing transcription factors. These transcription factors are known for their pivotal role in regulating gene expression during embryonic development, including the processes of cell differentiation, proliferation, and morphogenesis. The ARGFX protein, in particular, is believed to play a crucial role in early developmental stages, potentially influencing the formation and differentiation of various tissues. Although the detailed functions of ARGFX in human development remain to be fully elucidated, activators of this protein could provide valuable insights into its role in developmental processes and the regulation of gene expression patterns critical for early embryogenesis. By modulating the activity of ARGFX, these compounds could shed light on the intricate network of genetic pathways that govern developmental biology, contributing to a deeper understanding of the molecular mechanisms underlying tissue formation and cellular differentiation.
The investigation of ARGFX activators involves a comprehensive approach that combines synthetic chemistry, developmental biology, and molecular genetics. The development of these compounds requires an in-depth understanding of the structure and function of the ARGFX protein, particularly its DNA-binding domain and the specific sequences it targets within the genome. By designing molecules that can bind to and enhance the transcriptional activity of ARGFX, researchers aim to dissect the role of ARGFX-mediated gene regulation in development. This includes employing in vitro assays to assess the binding affinity and specificity of potential activators, as well as in vivo studies using model organisms to observe the effects of ARGFX activation on embryonic development. Techniques such as gene expression analysis, in situ hybridization, and phenotypic assessments are used to characterize the developmental outcomes of ARGFX activation, providing insights into its contribution to the formation of tissues and the orchestration of developmental processes. Through such multidisciplinary studies, the functional role of ARGFX in development can be better understood, enhancing our knowledge of the genetic and molecular basis of embryogenesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
May affect signaling pathways, leading to altered transcription factor activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Could modulate NF-κB pathways, possibly impacting gene regulation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Might influence SIRT1 pathways, affecting chromatin structure and gene expression. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
Flavonoid that may interact with estrogen receptors, potentially affecting gene transcription. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Could alter gene expression through its antioxidant properties affecting signaling pathways. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Flavonoid that might influence gene expression by affecting kinase signaling pathways. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $146.00 $582.00 $6248.00 | 4 | |
Antioxidant that may modulate gene expression through redox-sensitive pathways. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Polyphenol that could impact DNA methylation and histone modification. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Might induce antioxidant response elements in gene promoter regions. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Histone deacetylase inhibitor that can lead to epigenetic changes and gene expression. | ||||||