ANKRD42 Inhibitors
ANKRD42 Inhibitors encompass a variety of compounds that interfere with the cellular and molecular pathways that ANKRD42 may be involved in. These inhibitors function by targeting specific signaling cascades or cellular processes that are either directly regulated by ANKRD42 or are upstream of ANKRD42's point of action within the cell.
The inhibition of PI3K by compounds such as Wortmannin and LY294002 could lead to reduced ANKRD42 activity due to the central role of PI3K/AKT signaling in many cellular processes, including those that ANKRD42 may be involved in. By preventing the formation of PIP3, these inhibitors could reduce the activation of downstream effectors that are potentially important for ANKRD42 function. Similarly, mTOR signaling is crucial for protein synthesis and cellular growth, and the inhibition of mTOR by Rapamycin could suppress activities that are potentially regulated by ANKRD42.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor that blocks phosphorylation of PIP2 to PIP3, thus reducing AKT activity. Since ANKRD42 may be involved in pathways downstream of PI3K/AKT signaling, Wortmannin's inhibition of PI3K can lead to reduced ANKRD42 activity as a consequence of diminished AKT signaling. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another specific inhibitor of PI3K, LY294002 prevents the conversion of PIP2 to PIP3, which is essential for AKT activation. Reduced AKT signaling could lead to a decrease in ANKRD42 activity due to its potential involvement in PI3K/AKT mediated processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can suppress the mTORC1 complex, which is involved in protein synthesis and cell growth. If ANKRD42 function is tied to these cellular processes, Rapamycin can lead to decreased ANKRD42 activity by inhibiting mTORC1 signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor that can reduce the activity of p38 MAPK, a kinase involved in stress responses. If ANKRD42 is regulated by stress response pathways mediated by p38 MAPK, SB203580 could result in diminished ANKRD42 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An MEK inhibitor that blocks the MAPK/ERK pathway, which is involved in cell proliferation and differentiation. If ANKRD42 functions downstream of this pathway, inhibition by PD98059 could lead to decreased ANKRD42 activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A selective inhibitor of MEK1/2, preventing activation of the MAPK/ERK pathway. A decrease in ERK signaling can lead to reduced activity of ANKRD42 if it is part of this signaling cascade. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, which is involved in apoptosis and cell survival pathways. Inhibition of JNK by SP600125 could lead to a decrease in ANKRD42 activity if ANKRD42 is associated with JNK signaling. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor that impedes the function of Rho-associated protein kinase, affecting cytoskeletal dynamics and cell motility. If ANKRD42 is involved in these processes, its activity could be decreased by Y-27632. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Src family kinase inhibitor that can disrupt various signaling pathways including those involved in cell adhesion and migration. ANKRD42 activity could be decreased if it is associated with pathways regulated by Src kinases. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Proteasome inhibitor that can lead to the accumulation of misfolded proteins and disrupt cell signaling. If ANKRD42 is involved in pathways that are sensitive to proteostasis, Bortezomib could decrease its activity. | ||||||