Date published: 2026-4-1

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ANKK1 Inhibitors

ANKK1 inhibitors belong to a specialized class of chemical compounds designed to target and modulate the activity of ANKK1, which stands for Ankyrin Repeat and Kinase Domain Containing 1. ANKK1 is a protein that contains both ankyrin repeat domains, which are known for protein-protein interactions, and a kinase domain, suggesting potential roles in cellular signaling pathways. While the precise functions of ANKK1 are still under investigation, it has been implicated in various cellular processes, including potential involvement in protein-protein interactions, signal transduction, and cellular regulation. Inhibitors of ANKK1 are developed to interact with this specific protein, potentially influencing its kinase activity, interactions with binding partners, or its participation in cellular processes where ANKK1 is involved.

Structurally, ANKK1 inhibitors are carefully designed to engage specific regions or binding sites on the ANKK1 protein. This interaction may disrupt the normal functioning of ANKK1, potentially affecting its kinase-dependent signaling or its role in cellular regulation. The mechanisms by which ANKK1 inhibitors exert their effects can vary, but their primary objective is to serve as valuable tools for researchers studying the roles of ANKK1 in various cellular contexts. Investigating the biochemical and functional aspects of ANKK1 and its modulation by inhibitors can contribute to a deeper understanding of cellular signaling pathways, protein-protein interactions, and the broader field of molecular and cellular biology. Ultimately, such research can offer insights into the intricate molecular mechanisms that govern fundamental cellular functions and their potential regulation by ANKK1.

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Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$153.00
$396.00
113
(4)

A broad-spectrum kinase inhibitor which can inhibit many kinases, potentially influencing ANKK1 kinase activity.

H-89 dihydrochloride

130964-39-5sc-3537
sc-3537A
1 mg
10 mg
$94.00
$186.00
71
(2)

Known to inhibit various kinases and might affect signaling pathways involving ANKK1.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A PI3K inhibitor, affecting various signal transduction pathways, which could indirectly influence ANKK1.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor, influencing JNK signaling, which might have an effect on pathways involving ANKK1.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

A p38 MAPK inhibitor, it can affect p38 MAPK signaling, which could indirectly influence ANKK1.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor, which plays roles in multiple signaling pathways, potentially influencing ANKK1.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Another PI3K inhibitor, possibly affecting pathways that involve ANKK1.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

MEK inhibitor affecting the ERK pathway, which might influence pathways involving ANKK1.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

Inhibits NF-kB signaling, which could indirectly have effects on ANKK1 expression or activity.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

Rho-associated protein kinase (ROCK) inhibitor, possibly affecting signaling pathways that involve ANKK1.