ALS2CR16 Activators
ATP is fundamental to kinase activity, providing the phosphate groups that kinases transfer to proteins, such as ALS2CR16, to modify their activity. Sodium Orthovanadate acts to maintain proteins in a phosphorylated state by inhibiting the action of phosphatases, thereby preserving the functional state of proteins like ALS2CR16. On the genetic level, 5-Azacytidine can lead to the upregulation of gene expression by preventing methylation, which could enhance the transcription of the ALS2CR16 gene. Similarly, Trichostatin A can increase gene transcription by promoting histone acetylation, potentially leading to greater expression of ALS2CR16.
Retinoic Acid and Lithium Chloride can influence gene expression and protein stability by engaging with nuclear receptors and inhibitory pathways, respectively. Compounds like Forskolin and Dibutyryl cAMP elevate intracellular cAMP levels, which activate PKA and can lead to enhanced phosphorylation and activity of ALS2CR16. Growth factors such as EGF and NGF bind to their respective receptors, initiating signaling cascades that could culminate in increased ALS2CR16 activity. Insulin and PDGF might also play a role by activating pathways that promote cell survival and proliferation, which could indirectly stabilize ALS2CR16 expression or activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ATP | 56-65-5 | sc-507511 | 5 g | $17.00 | ||
Serves as a substrate for kinases which can phosphorylate proteins, potentially affecting ALS2CR16 by altering its phosphorylation state. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $45.00 $56.00 $183.00 | 142 | |
Acts as a phosphatase inhibitor, which can prevent dephosphorylation of proteins, potentially maintaining ALS2CR16 in an active state. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, which can lead to the demethylation of genes, possibly upregulating the expression of ALS2CR16. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Inhibits histone deacetylases (HDAC), which can result in hyperacetylation of histones and potentially increase the transcription of ALS2CR16. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Can regulate gene expression through retinoic acid receptors, possibly enhancing the transcription of ALS2CR16. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Inhibits GSK-3β, which can lead to the activation of the Wnt signaling pathway, potentially influencing the expression or activity of ALS2CR16. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases cAMP, potentially activating PKA and affecting the phosphorylation and activity of ALS2CR16. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Can activate the PI3K/Akt signaling pathway, which may lead to increased survival signaling that potentially enhances the stability or expression of ALS2CR16. | ||||||
PDGFR Tyrosine Kinase Inhibitor IV | 627518-40-5 | sc-205794 sc-205794A sc-205794B sc-205794C | 1 mg 5 mg 10 mg 50 mg | $27.00 $138.00 $257.00 $1127.00 | 2 | |
Binds to its receptor, potentially activating downstream signaling cascades that could influence the activity or expression of ALS2CR16. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
A cAMP analog that can activate PKA, potentially leading to changes in phosphorylation patterns affecting ALS2CR16. | ||||||