ALS Inhibitors
Insulin-like growth factor binding protein acid labile subunit (IGFALS) inhibitors constitute a class of chemical compounds specifically engineered to modulate the activity of the IGFALS protein. IGFALS is a crucial component of the insulin-like growth factor (IGF) system, playing a significant role in the regulation of IGF bioavailability and function. These inhibitors are primarily employed in molecular and cellular biology research to elucidate the functional properties and regulatory mechanisms associated with the IGFALS protein.
The development of IGFALS inhibitors typically involves a combination of biochemical and structural approaches aimed at identifying or designing molecules that can selectively interact with IGFALS and influence its activity. By targeting IGFALS, these inhibitors have the potential to impact the binding and transport of IGFs, which are vital growth factors involved in various physiological processes. Researchers use IGFALS inhibitors to explore the intricate roles played by IGFALS in regulating IGF signaling pathways, allowing for a deeper understanding of its contributions to cellular functions and metabolism.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea can inhibit ribonucleotide reductase, affecting DNA synthesis, which may indirectly influence gene expression and protein synthesis. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Sirolimus, also known as Rapamycin, inhibits mTOR, which is a central regulator of cell growth and protein synthesis. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin is known to modulate various signaling pathways and might affect gene expression related to these pathways. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
As an isoflavone, genistein can modulate several signal transduction pathways, potentially influencing gene expression and protein synthesis. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol affects sirtuins and other signaling pathways, which can modulate gene expression and protein synthesis. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Sodium butyrate acts as a histone deacetylase inhibitor, affecting chromatin structure and gene expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
This compound inhibits Topoisomerase I, influencing DNA replication and transcription, thus affecting protein synthesis. | ||||||
Emetine | 483-18-1 | sc-470668 sc-470668A sc-470668B sc-470668C | 1 mg 10 mg 50 mg 100 mg | $352.00 $566.00 $1331.00 $2453.00 | ||
Emetine inhibits eukaryotic protein synthesis by blocking the movement of the ribosome along mRNA. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Mitomycin C forms crosslinks in DNA, which can inhibit DNA synthesis and thus protein expression. | ||||||
Allicin | 539-86-6 | sc-202449 sc-202449A | 1 mg 5 mg | $460.00 $1428.00 | 7 | |
Allicin, found in garlic, can modulate various cellular processes and potentially influence protein expression. | ||||||