α1D-AR Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(R)-(−)-Phenylephrine hydrochloride | 61-76-7 | sc-203677 sc-203677A | 100 mg 5 g | $50.00 $66.00 | 1 | |
(R)-(-)-Phenylephrine hydrochloride acts as a selective alpha1D-adrenergic receptor agonist, exhibiting unique stereochemical properties that enhance its binding affinity. Its molecular conformation allows for optimal interactions with the receptor's active site, triggering specific conformational changes that activate intracellular signaling pathways. The compound's kinetic profile reveals a fast onset of action, coupled with a prolonged receptor engagement, highlighting its role in modulating vascular tone and smooth muscle contraction. | ||||||
L-Noradrenaline | 51-41-2 | sc-357366 sc-357366A | 1 g 5 g | $326.00 $485.00 | 3 | |
A natural neurotransmitter and hormone that acts as a general agonist for alpha-1 adrenergic receptors. | ||||||
Terazosin hydrochloride | 63074-08-8 | sc-204337 | 50 mg | $117.00 | ||
Terazosin hydrochloride functions as a selective alpha1D-adrenergic receptor antagonist, characterized by its ability to stabilize receptor conformation through unique hydrogen bonding interactions. This compound exhibits a distinct affinity for the receptor's allosteric sites, influencing downstream signaling cascades. Its kinetic behavior demonstrates a gradual dissociation rate, allowing for sustained modulation of receptor activity, which can impact various physiological processes. The compound's lipophilicity enhances membrane permeability, facilitating its interaction with lipid bilayers. | ||||||
L-phenylephrine | 59-42-7 | sc-295315 sc-295315A | 5 g 25 g | $181.00 $492.00 | 2 | |
A selective α1-agonist commonly used in nasal decongestants; interacts with α1D-AR. | ||||||
A 61603 HYDROBROMIDE | 107756-30-9 | sc-203789 sc-203789A | 10 mg 50 mg | $398.00 $1607.00 | ||
A 61603 HYDROBROMIDE acts as a selective alpha1D-adrenergic receptor antagonist, notable for its unique electrostatic interactions that enhance receptor binding affinity. This compound exhibits a rapid onset of action due to its efficient conformational adaptation within the receptor's binding pocket. Its distinct solubility profile allows for effective distribution in biological systems, while its kinetic properties reveal a complex interplay of receptor desensitization and resensitization, influencing overall receptor dynamics. | ||||||
Xylometazoline hydrochloride | 1218-35-5 | sc-255719 | 5 g | $164.00 | ||
Xylometazoline hydrochloride functions as a selective alpha1D-adrenergic receptor agonist, characterized by its ability to induce conformational changes in the receptor that promote signal transduction. Its molecular structure facilitates strong hydrophobic interactions, enhancing binding stability. The compound exhibits a unique pharmacokinetic profile, with a rapid dissociation rate from the receptor, allowing for transient modulation of adrenergic signaling pathways. Additionally, its solubility characteristics contribute to its distribution in various environments. | ||||||
DL-Phenylephrine Hydrochloride | 154-86-9 | sc-294407 | 25 g | $179.00 | ||
DL-Phenylephrine Hydrochloride acts as a potent alpha1D-adrenergic receptor agonist, exhibiting unique stereochemical properties that influence receptor affinity and selectivity. Its molecular interactions are marked by specific hydrogen bonding and ionic interactions, which enhance receptor activation. The compound's kinetic behavior reveals a notable rate of receptor engagement, allowing for precise modulation of downstream signaling cascades. Furthermore, its solubility in polar solvents aids in its distribution across biological membranes. | ||||||
Midodrine, Hydrochloride | 3092-17-9 | sc-211910 | 10 mg | $187.00 | ||
Prodrug of desglymidodrine, which is an agonist for alpha-1 adrenergic receptors. | ||||||
Amezinium Methyl Sulfate | 30578-37-1 | sc-487577 | 1 g | $152.00 | ||
A sympathomimetic drug with agonistic action on alpha-1 adrenergic receptors. | ||||||