alpha1D-AR Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
RS 102895 Hydrochloride | 300815-41-2 | sc-204243 sc-204243A | 10 mg 50 mg | $128.00 $505.00 | 5 | |
RS 102895 Hydrochloride is a selective alpha1D-adrenergic receptor antagonist, characterized by its unique binding dynamics that favor specific conformational changes in the receptor. This compound exhibits distinct hydrophobic interactions that stabilize its complex with the receptor, influencing downstream signaling pathways. Its rapid dissociation kinetics allow for fine-tuning of receptor activity, while its solubility profile enhances its interaction with lipid membranes, facilitating effective cellular uptake. | ||||||
Carvedilol | 72956-09-3 | sc-200157 sc-200157A sc-200157B sc-200157C sc-200157D | 100 mg 1 g 10 g 25 g 100 g | $124.00 $240.00 $530.00 $999.00 $1530.00 | 2 | |
Carvedilol acts as an alpha1D-adrenergic receptor modulator, exhibiting a unique dual binding mechanism that engages both hydrophilic and hydrophobic regions of the receptor. This compound induces specific allosteric changes, enhancing receptor desensitization and altering signal transduction pathways. Its favorable lipophilicity promotes membrane permeability, while its kinetic profile allows for a nuanced modulation of receptor activity, impacting cellular responses effectively. | ||||||
BMY 7378 dihydrochloride | 21102-95-4 | sc-203849 sc-203849A | 10 mg 50 mg | $99.00 $308.00 | ||
BMY 7378 dihydrochloride selectively targets the alpha1D-adrenergic receptor, demonstrating a unique affinity for specific binding sites that stabilize receptor conformation. This compound influences downstream signaling cascades by modulating G-protein coupling efficiency, leading to distinct cellular responses. Its structural characteristics facilitate interactions with lipid bilayers, enhancing bioavailability and influencing receptor dynamics. The compound's kinetic behavior allows for precise temporal control of receptor activation, contributing to its unique pharmacological profile. | ||||||
Benoxathian hydrochloride | 92642-97-2 | sc-254954 | 10 mg | $92.00 | ||
Benoxathian hydrochloride exhibits a selective interaction with the alpha1D-adrenergic receptor, characterized by its ability to induce conformational changes that enhance receptor activation. This compound engages in unique hydrogen bonding and hydrophobic interactions, promoting stability in receptor-ligand complexes. Its distinct molecular structure allows for efficient penetration through cellular membranes, influencing receptor localization and signaling pathways. The compound's reaction kinetics reveal a rapid onset of action, underscoring its dynamic role in modulating adrenergic signaling. | ||||||
Terazosin Hydrochloride dihydrate | 70024-40-7 | sc-205857 sc-205857A | 50 mg 250 mg | $112.00 $444.00 | ||
Terazosin Hydrochloride dihydrate selectively targets the alpha1D-adrenergic receptor, facilitating unique allosteric modulation that alters receptor dynamics. Its molecular architecture supports specific ionic interactions and steric effects, enhancing binding affinity. The compound's solubility characteristics promote effective diffusion across lipid bilayers, impacting cellular uptake and receptor distribution. Kinetic studies indicate a gradual dissociation profile, reflecting its sustained influence on adrenergic pathways. | ||||||