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Terazosin Hydrochloride dihydrate (CAS 70024-40-7)

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Alternate Names:
Heitrin; Hytracin
Application:
Terazosin Hydrochloride dihydrate is an α1-selective blocker
CAS Number:
70024-40-7
Purity:
≥98%
Molecular Weight:
459.93
Molecular Formula:
C19H25N5O4 HCl 2H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Terazosin Hydrochloride dihydrate is an a1-selective blocker. Its inhibitory effect on prostate tumor growth may be the result of antiangiogenic activity. Terazosin Hydrochloride dihydrate is an inhibitor of α1A-AR, α1B-AR, α1D-AR and α2B-AR.


Terazosin Hydrochloride dihydrate (CAS 70024-40-7) References

  1. Identification of apoptotic and antiangiogenic activities of terazosin in human prostate cancer and endothelial cells.  |  Pan, SL., et al. 2003. J Urol. 169: 724-9. PMID: 12544352
  2. Renal hemodynamic responses to 5-hydroxytryptamine (5-HT): involvement of the 5-HT receptor subtypes in the canine kidney.  |  Shoji, T., et al. 1989. Eur J Pharmacol. 171: 219-28. PMID: 2576001
  3. Pharmacology of terazosin: an alpha 1-selective blocker.  |  Kyncl, JJ. 1993. J Clin Pharmacol. 33: 878-83. PMID: 7901242
  4. Potentiometric and Fluorimetric Methods for the Determination of Terazosin HCl in Drug Substance and Dosage Forms  |  Ismail, N. S., & Mohamed, T. A. 2014. International Journal of Electrochemical Science. 9(12): 7394-7413.
  5. Crystal structure of terazosin hydrochloride dihydrate (Hytrin®), C19H26N5O4Cl (H2O) 2  |  Wheatley, A. M., Kaduk, J. A., Vickers, M., Gindhart, A. M., Sunzeri, J. G., & Blanton, T. N. 2018. Powder Diffraction. 33(3): 229-236.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Terazosin Hydrochloride dihydrate, 50 mg

sc-205857
50 mg
$112.00

Terazosin Hydrochloride dihydrate, 250 mg

sc-205857A
250 mg
$444.00