Xylometazoline hydrochloride CAS: 1218-35-5
MF: C16H24N2•HCl
MW: 280.84
An α-adrenoceptor agonist.

Xylometazoline hydrochloride (CAS 1218-35-5)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 103ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Alternate Names: 2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride
Application: Xylometazoline hydrochloride is α-adrenoceptor agonist
CAS Number: 1218-35-5
Purity: ≥98%
Molecular Weight: 280.84
Molecular Formula: C16H24N2•HCl
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Xylometazoline hydrochloride, α-adrenoceptor agonist; imidazoline binding site ligand. Xylometazoline hydrochloride is an activator of α1A-AR, α1B-AR, α1D-AR, α2A-AR, α2B-AR and α2C-AR.


References

Sakuta, H., and Okamoto, K., Inhibition by imidazoline and imidazolidine derivatives of glibenclamide-sensitive K+ currents in Xenopus oocytes. Eur. J. Pharmacol. 259, 223-231, (1994) Bognar, I.T., et al., å-adrenoceptor mediated facilitation of acetylcholine release in the rat perfused heart. J. Pharmacol. Exp. Ther. 254, 702, (1990)

Physical State :
Solid
Solubility :
Soluble in ethanol (100 mg/ml), and DMSO (27 mg/ml at 25° C).
Storage :
Store at room temperature
Refractive Index :
n20D ~1.54 (Predicted)
IC50 :
α1A-AR: IC50 = 0.08 µM; α2C-AR: IC50 = 0.22 µM; α1D-AR: IC50 = 0.45 µM; α1B-AR: IC50 = 0.56 µM; α2A-AR: IC50 = 0.98 µM
Ki Data :
SR-1D: Ki= 0.7 nM (human); SR-1B: Ki= 13 nM (human); α1A-AR: Ki= 91 nM (human); Adrenergic receptor α: Ki= 91 nM (huamn); Adrenergic receptor α-2: Ki>500 nM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
NJ2390000
Transport :
UN 2811, Class 6.1, Packing group III
PubChem CID :
5282386
Merck Index :
14: 10086
MDL Number :
MFCD00238707
EC Number :
214-936-4
SMILES :
CC1=CC(=CC(=C1CC2=NCCN2)C)C(C)(C)C.Cl

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 119ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.