Terazosin hydrochloride CAS: 63074-08-8
MF: C19H25N5O4•HCl
MW: 423.9
An α1- and α2B-adrenoceptor antagonist.

Terazosin hydrochloride (CAS 63074-08-8)

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Application: Terazosin hydrochloride is an α1- and α2B-adrenoceptor antagonist
CAS Number: 63074-08-8
Purity: ≥98%
Molecular Weight: 423.9
Molecular Formula: C19H25N5O4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Terazosin hydrochloride acts as an α1- and α2B-adrenoceptor antagonist (Ki values are 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α1A, α1B, α1D, α2B, α2A and α2C receptors respectively).


References

Kyncl (1986) Pharmacology of terazosin. Am.J.Med. 80 12. Maruyama et al (1994) Comparison of displacemental potencies of terazosin enantiomers for a1-adrenoceptor subtypes. Biol.Pharm.Bull. 17 1126. Hancock et al (1995) Actions of terazosin and its enantiomers at subtypes of a1- and a2-adrenoceptors in vitro. J.Rec.Signal Transduct.Res. 15 863.

Physical State :
Solid
Solubility :
Soluble to 50 mM in Water
Storage :
Store at room temperature
Melting Point :
261-263° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
44383
SMILES :
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.Cl

Download SDS (MSDS)

Certificate of Analysis

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