α E-catenin Activators
α E-catenin activators are a class of chemical compounds that exert their effects on a specific protein known as α E-catenin. These activators are of particular interest due to their role in regulating cellular processes involved in cell adhesion, cell migration, and tissue development. α E-catenin is a key component of the cadherin-catenin complex, which plays a crucial role in cell-cell adhesion and maintaining tissue integrity. It functions as a link between the cadherin adhesion receptors and the actin cytoskeleton, facilitating the formation of adherens junctions between adjacent cells.
The activation of α E-catenin by these chemical compounds involves a conformational change in the protein, allowing it to more effectively bind to F-actin, a protein filament within the cell's cytoskeleton. This enhanced interaction between α E-catenin and F-actin promotes the stabilization of cell-cell adhesions and can impact various cellular processes such as embryonic development, tissue morphogenesis, and wound healing. Additionally, α E-catenin activators have been studied for their potential in influencing cell migration, as increased α E-catenin activity may limit cell motility by strengthening cell-cell adhesions. Understanding the mechanisms and implications of α E-catenin activation is of great importance in the fields of cell biology and developmental biology, as it sheds light on the intricate processes governing tissue formation and maintenance. Further research into the precise mechanisms of α E-catenin activation by these compounds may offer insights into fundamental cellular processes and potential applications in various areas of biological research.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid is a derivative of vitamin A and plays a crucial role in cell growth, differentiation, and apoptosis. It has been shown to modulate gene expression, potentially upregulating α E-catenin to promote cell adhesion and tissue integrity. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane is a compound found in cruciferous vegetables. It may upregulate α E-catenin through its role in detoxification and antioxidant defense, contributing to cellular protection and stability. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Derived from turmeric, curcumin has anti-inflammatory and antioxidant properties. It may induce α E-catenin expression as part of a cellular response to reduce oxidative stress and maintain cell integrity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Found in grapes and berries, resveratrol has antioxidant properties. It may increase α E-catenin expression as part of a protective cellular response against oxidative damage, promoting cell adhesion and stability. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 plays a role in cell growth and differentiation. It may induce α E-catenin expression to support cell-cell adhesion and maintain tissue integrity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A major component of green tea, it may upregulate α E-catenin expression as part of a cellular defense mechanism against oxidative stress. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid found in many fruits and vegetables, quercetin has antioxidant properties. It may induce α E-catenin expression to protect cells from oxidative stress and maintain tissue stability. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
An essential mineral, zinc plays a role in cell growth and differentiation. It may upregulate α E-catenin expression to support cell adhesion and tissue integrity. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $62.00 | 1 | |
An essential trace element, selenium is crucial for proper cellular function. It may induce α E-catenin expression as part of its role in antioxidant defense and maintaining cell integrity. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $146.00 $582.00 $6248.00 | 4 | |
Found in tomatoes and other red fruits, lycopene has antioxidant properties. It may increase α E-catenin expression to protect cells from oxidative damage and support tissue stability. | ||||||