ALG-2 Activators
Programmed cell death 6-interacting protein (PDCD6IP), also known as ALIX (ALG-2-interacting protein X), is involved in several cellular processes, including endosomal sorting, membrane repair, and cell death pathways. It is associated with the Endosomal Sorting Complex Required for Transport (ESCRT) machinery and is important for the abscission step during cytokinesis and in the budding of certain enveloped viruses.
Activators for such proteins, as in the case with many regulatory or scaffolding proteins, typically do not consist of small chemical molecules but are rather other proteins or lipids that interact with the scaffolding protein to modulate its function. However, considering small molecule compounds that could indirectly influence the activity of PDCD6IP through related pathways or cellular processes, we must proceed with caution as this enters the realm of speculation and these interactions would not be well-established. Another category of ALG-2 activators includes peptides found in the ALG-2 binding partners. These peptides can mimic the natural interactions of ALG-2 with its target proteins, enhancing the formation of functional complexes. Through this mechanism, ALG-2 activators can influence various cellular processes, such as endosomal sorting and membrane trafficking. The small molecules and peptides that fall within the ALG-2 activator class can thus act as molecular modulators, enhancing the specific functions associated with ALG-2 in a controlled and regulated manner.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
This compound increases intracellular calcium levels, which could affect calcium-binding proteins like ALG-2, potentially modulating the interaction with PDCD6IP. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
LPA is a bioactive lipid that can act as a signaling molecule and influence various cellular processes, including those that might intersect with PDCD6IP's functions. | ||||||
Urolithin A | 1143-70-0 | sc-475514 sc-475514A sc-475514B sc-475514C | 25 mg 100 mg 1 g 5 g | $204.00 $459.00 $714.00 $1224.00 | 10 | |
Urolithin A is a metabolite compound that has been shown to induce autophagy, a process with which PDCD6IP is interconnected through its role in membrane dynamics. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is an activator of adenylyl cyclase, leading to increased levels of cAMP, which can influence various signaling pathways and may have downstream effects on proteins like PDCD6IP. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a diacylglycerol analog that activates protein kinase C (PKC) and can modulate numerous signaling pathways, potentially influencing PDCD6IP's activity in the process. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
S1P is a signaling sphingolipid that can influence cytoskeletal rearrangements and vesicular trafficking, which could indirectly affect PDCD6IP function. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate multiple signaling pathways and might influence the broader regulatory context in which PDCD6IP operates, including apoptosis and cell survival signals. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $110.00 $150.00 $220.00 $300.00 $600.00 | 4 | |
NMN is a precursor of NAD+ and can influence cellular metabolism and energy status, which could potentially impact PDCD6IP's role in the cell, given the energy dependence of the ESCRT machinery. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol impacts several signaling pathways and could affect cellular processes such as apoptosis and autophagy, potentially influencing PDCD6IP activity. | ||||||