Date published: 2025-12-7

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ALCAM Inhibitors

ALCAM (Activated Leukocyte Cell Adhesion Molecule), also known as CD166, is a cell surface glycoprotein belonging to the immunoglobulin superfamily. ALCAM plays a crucial role in various cellular processes, primarily by mediating cell-cell adhesion and promoting cell migration. ALCAM is widely expressed in different tissues and cell types, including leukocytes, neurons, and endothelial cells. In recent years, researchers have identified a class of compounds known as ALCAM inhibitors, which are designed to modulate the function of this cell adhesion molecule. ALCAM inhibitors are chemical compounds or biologics that target ALCAM and interfere with its activity. These inhibitors work by binding to specific regions on ALCAM's extracellular domain, preventing its interaction with other cell surface molecules or extracellular ligands. By inhibiting ALCAM, these compounds can impact various physiological and pathological processes where ALCAM-mediated cell adhesion and signaling play a role. ALCAM inhibitors have garnered attention in the field of research for their ability to influence cell migration, immune cell activation, and neural development, among other cellular events.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin, a polyphenolic compound found in turmeric, may downregulate ALCAM expression through its anti-inflammatory and antioxidant properties. It modulates various signaling pathways and transcription factors, potentially leading to reduced ALCAM levels.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol, found in grapes and red wine, is known for its antioxidant and anti-inflammatory effects. It may inhibit ALCAM expression by modulating signaling pathways.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin, a flavonoid present in many fruits and vegetables, possesses anti-inflammatory and antioxidant properties. It may influence ALCAM expression by modulating cellular signaling pathways and reducing oxidative stress.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

Sulforaphane, found in cruciferous vegetables, is recognized for its potential anti-cancer properties. It might inhibit ALCAM expression by inducing detoxification enzymes and suppressing inflammation.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein, a soy-derived isoflavone, is known for its antioxidant and anti-inflammatory effects. It may suppress ALCAM expression through modulating estrogen receptor signaling and influencing various cellular pathways.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG, the major catechin in green tea, has demonstrated antioxidant and anti-inflammatory properties. It may inhibit ALCAM expression by modulating cellular signaling pathways.

L-Ascorbic acid, free acid

50-81-7sc-202686
100 g
$45.00
5
(1)

Vitamin C, a well-known antioxidant, can potentially reduce ALCAM expression through its ability to scavenge reactive oxygen species and modulate various signaling pathways.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

Vitamin D, essential for calcium homeostasis, also has immunomodulatory effects. It might suppress ALCAM expression by modulating immune responses and influencing gene expression through its receptor.

Fisetin

528-48-3sc-276440
sc-276440A
sc-276440B
sc-276440C
sc-276440D
50 mg
100 mg
500 mg
1 g
100 g
$51.00
$77.00
$102.00
$153.00
$2856.00
7
(1)

Fisetin, a flavonol found in various fruits and vegetables, exhibits antioxidant and anti-inflammatory effects. It may inhibit ALCAM expression through modulating cellular signaling pathways.

β-Carotene

7235-40-7sc-202485
sc-202485A
sc-202485B
sc-202485C
1 g
25 g
50 g
5 kg
$68.00
$297.00
$502.00
$12246.00
5
(1)

Beta-carotene, a precursor of vitamin A, is an antioxidant that may downregulate ALCAM expression through its ability to neutralize reactive oxygen species and influence gene expression.