Ajuba Activators
Ajuba activators, as listed, are primarily chemicals that indirectly affect Ajuba activity by targeting signaling pathways, cytoskeletal dynamics, or cell adhesion mechanisms relevant to its function. Ajuba functions as a scaffold protein, integrating various signaling pathways and playing a role in cytoskeletal organization. The chemicals mentioned, such as kinase inhibitors (Y-27632, PD98059, LY294002, SB203580), cytoskeletal modulators (Blebbistatin, Nocodazole, Latrunculin A, Jasplakinolide), and signaling pathway activators or inhibitors (Forskolin, Wnt Agonist, TGF-β Inhibitor), act on different aspects of cellular signaling and structural organization, potentially influencing the function of Ajuba.
These activators are significant in understanding the complex interactions within signaling networks and the cytoskeleton. Modulating pathways like MAPK, PI3K, or Wnt can impact the cellular context in which Ajuba operates, thereby influencing its role in these processes. For example, affecting cytoskeletal dynamics can have downstream effects on Ajuba's function in cell migration and adhesion.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 inhibits ROCK, a kinase involved in cytoskeletal dynamics, potentially impacting processes where Ajuba is involved. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which can modulate various signaling pathways, including those related to Ajuba. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an inhibitor of MEK, a kinase in the MAPK pathway, potentially influencing signaling networks involving Ajuba. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor, affecting intracellular signaling that could intersect with Ajuba's role in cell signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 inhibits p38 MAPK, potentially impacting signaling pathways and cellular processes involving Ajuba. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $71.00 $260.00 $485.00 $949.00 | ||
Blebbistatin inhibits myosin II, potentially affecting cytoskeletal interactions and processes where Ajuba is involved. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubules, potentially affecting cellular transport mechanisms and cytoskeletal organization where Ajuba functions. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Latrunculin A disrupts actin filaments, potentially influencing cytoskeletal dynamics related to Ajuba's function. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $180.00 $299.00 | 59 | |
Jasplakinolide stabilizes actin filaments, which could indirectly impact processes involving Ajuba. | ||||||
Wnt Agonist | 853220-52-7 | sc-222416 sc-222416A | 5 mg 25 mg | $154.00 $597.00 | 23 | |
SKL2001 activates the Wnt/β-catenin signaling pathway, potentially influencing Ajuba-related pathways. | ||||||