AI480653 Activators
AI480653 Activators encompass a range of chemical compounds that each influence distinct biochemical pathways, cumulatively leading to the enhanced functional activity of AI480653. Forskolin and Sildenafil elevate intracellular levels of cAMP and cGMP, respectively, which can activate protein kinase A (PKA) or prevent the breakdown of these signaling molecules, potentially enhancing the activity of AI480653 if it is regulated by these pathways. AI480653 Activators are a group of chemical compounds that enhance the functional activity of the protein AI480653 through various signaling pathways and cellular processes. Compounds such as Forskolin and Sildenafil act to elevate the levels of cAMP and cGMP respectively, which could lead to the activation of PKA or prevent the breakdown of these cyclic nucleotides, thus indirectly leading to enhanced AI480653 activity if it is regulated by these second messengers.
Similarly, Epigallocatechin gallate (EGCG) and Resveratrol may indirectly enhance AI480653 by modulating kinase activity or by altering the acetylation state of proteins, respectively, which suggests their potential to lift regulatory constraints on AI480653 activity, assuming it is affected by such post-translational modifications. Other activators like Curcumin and Sodium butyrate could enhance AI480653 activity through modulation of transcription factors such as NF-kB, or by epigenetic mechanisms involving histone deacetylation, which would increase AI480653 expression if it is under such control. Compounds including Retinoic acid and Pioglitazone could enhance AI480653 activity by affecting gene expression through retinoic acid receptors or PPAR-gamma, assuming AI480653 is regulated by these nuclear receptor pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin directly stimulates adenylyl cyclase, increasing intracellular cAMP levels. Elevated cAMP activates PKA, which can then phosphorylate specific substrates leading to enhanced AI480653 activity if its function is regulated by cAMP-dependent phosphorylation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG inhibits multiple protein kinases, altering signaling cascades. If AI480653 is negatively regulated by a kinase that EGCG inhibits, its activity would be enhanced by a reduction in this inhibitory phosphorylation. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates sirtuins, particularly SIRT1, which can deacetylate proteins and affect their activity. If AI480653 is regulated by acetylation, resveratrol could enhance its activity through deacetylation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin influences multiple signaling pathways, including the inhibition of NF-kB. If AI480653's activity is suppressed by NF-kB pathway signaling, curcumin would enhance AI480653 by alleviating this suppression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate is a histone deacetylase inhibitor, which can lead to a more relaxed chromatin structure and potentially increased gene expression. If the expression of AI480653 is limited by histone acetylation levels, sodium butyrate could enhance its activity by increasing its expression. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid binds to and activates retinoic acid receptors, which can influence gene expression. If AI480653 is positively regulated by retinoic acid receptor signaling, its activity would be enhanced by retinoic acid. | ||||||
Pioglitazone hydrochloride | 112529-15-4 | sc-204848 sc-204848A | 100 mg 500 mg | $62.00 $209.00 | 19 | |
Pioglitazone is a PPAR-gamma agonist, which modulates the transcription of genes involved in metabolism. If AI480653 activity is linked to metabolic pathways regulated by PPAR-gamma, pioglitazone would enhance AI480653 activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium inhibits GSK-3, which may lead to the stabilization and activation of proteins regulated by GSK-3 mediated phosphorylation. If AI480653 is negatively regulated by GSK-3, lithium would enhance its activity. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin activates TRPV1, which can lead to downstream effects on cellular signaling pathways, including calcium influx. If AI480653's activity is regulated by calcium signaling or TRPV1, capsaicin could enhance AI480653. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium concentration. If AI480653 is regulated by calcium-dependent signaling pathways, ionomycin would enhance AI480653 activity by increasing intracellular calcium. | ||||||