AGAP1 Inhibitors
AGAP1 Inhibitorsare associated with the intricate web of cellular processes related to vesicular trafficking, cytoskeletal dynamics, and Arf-related pathways in which AGAP1 operates. Brefeldin A, for instance, is renowned for disturbing the Golgi apparatus by inhibiting Arf1, casting an indirect influence on AGAP1's role in vesicular trafficking. Similarly, SecinH3 is a specific inhibitor of cytohesin ArfGEFs, thus affecting the activation of Arf and potentially AGAP1's actions within the cell.
On the endocytic front, chemicals like Exo2 and Dynasore act as disruptors. While Exo2 perturbs general endocytosis and vesicle trafficking pathways, Dynasore specifically targets dynamin, a GTPase involved in the scission of vesicles during endocytosis. This class of inhibitors provides a crucial toolset to understand the broader landscape of cellular processes where AGAP1 operates, even indirectly. Furthermore, the action of chemicals like CK666 and SMIFH2, which respectively inhibit the Arp2/3 complex and formins, underscores the importance of actin dynamics in understanding AGAP1's cellular role.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disturbs the Golgi apparatus by inhibiting Arf1, potentially affecting AGAP1's role in vesicular trafficking. | ||||||
SecinH3 | 853625-60-2 | sc-203260 | 5 mg | $273.00 | 6 | |
A specific inhibitor of cytohesin ArfGEFs, influencing Arf activation and potentially AGAP1's actions. | ||||||
Golgicide A | 1005036-73-6 | sc-215103 sc-215103A | 5 mg 25 mg | $187.00 $670.00 | 11 | |
A potent and selective Arf1 GEF inhibitor, disrupting the Golgi and potentially impacting AGAP1 functionality. | ||||||
Exo2 | 304684-77-3 | sc-215011 sc-215011A | 5 mg 25 mg | $87.00 $282.00 | 1 | |
Disturbs endocytosis and vesicle trafficking, indirectly affecting pathways where AGAP1 might be involved. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
A non-competitive inhibitor of dynamin, impacting endocytosis and processes associated with AGAP1. | ||||||
Pitstop 2 | 1419093-54-1 | sc-507418 | 10 mg | $360.00 | ||
Inhibits clathrin-mediated endocytosis, a pathway where AGAP1 can play a role. | ||||||
Phenylarsine oxide | 637-03-6 | sc-3521 | 250 mg | $40.00 | 4 | |
Inhibits protein tyrosine phosphatases, affecting multiple signaling pathways that might intersect with AGAP1's role. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $134.00 $502.00 | 7 | |
Cdc42 inhibitor affecting cytoskeletal dynamics which can intersect with the functional scope of AGAP1. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $315.00 $1020.00 | 5 | |
Inhibits Arp2/3 complex, impacting actin polymerization and cytoskeletal dynamics where AGAP1 might be active. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
Inhibits formins, affecting actin polymerization processes potentially related to AGAP1's cellular role. | ||||||