Molecular structure of Exo2, CAS Number: 304684-77-3
Exo2 (CAS 304684-77-3)
See product citations (1)
Alternate Names:
2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol
Application:
Exo2 is a compound used as a probe of intracellular transport
CAS Number:
304684-77-3
Molecular Weight:
354.43
Molecular Formula:
C18H18N4O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Acts as a chemical probe of intracellular transport. The compound has activities similar to Brefeldin A with membrane trafficking to the Golgi appartus, but seems to be more selective.
Exo2 (CAS 304684-77-3) References
The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochem. J. 414, 471-484, (2008); Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells. EMBO Rep. 5, 596-601, (2004)Inhibitor of:
β′-COP, ACBD3, ADP-ribosylation factor (ARF), AGAP1, AP3 Adaptor Complex, ARF1, ARFGAP, ARFGAP2, ARFGEF (BIG1, BIG2, BIG3), ARFRP1, ARL4, ARL5A, ARNO, copGFP, COPZ, D030016E14Rik, E430025E21Rik, Erd2, Gm949, GOLGA6L10, GOLGA8O, GOLPH3, MCFD2, Mex3d, POR1, RAB 11B, Rab 40AL, TBC1D2, TBPIP, TMED7, TMP21, TRAPPC6B, VAMP-1, and ZASC1.Activator of:
Shigatoxin 1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Exo2, 5 mg | sc-215011 | 5 mg | $89.00 | |||
Exo2, 25 mg | sc-215011A | 25 mg | $288.00 |