Exo2 CAS: 304684-77-3
MF: C18H18N4O2S
MW: 354.43
A compound used as a probe of intracellular transport.

Exo2 (CAS 304684-77-3)

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Alternate Names: 2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol
Application: Exo2 is a compound used as a probe of intracellular transport
CAS Number: 304684-77-3
Molecular Weight: 354.43
Molecular Formula: C18H18N4O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Acts as a chemical probe of intracellular transport. The compound has activities similar to Brefeldin A with membrane trafficking to the Golgi appartus, but seems to be more selective.


References

The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochem. J. 414, 471-484, (2008); Retrograde transport of cholera toxin from the plasma membrane to the endoplasmic reticulum requires the trans-Golgi network but not the Golgi apparatus in Exo2-treated cells. EMBO Rep. 5, 596-601, (2004)

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in DMSO (>20 mg/mL).
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
6815276
MDL Number :
MFCD00380179
SMILES :
COc1cc(C=NNc2ncnc3c2c2CCCCc2s3)ccc1O

Download SDS (MSDS)

Certificate of Analysis

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