ADK Inhibitors
Items 1 to 10 of 16 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $45.00 $56.00 $183.00 | 142 | |
Sodium Orthovanadate acts as a potent inhibitor of protein tyrosine phosphatases, influencing cellular signaling pathways. Its unique ability to mimic phosphate groups allows it to interact with various enzymes, altering phosphorylation states and modulating signal transduction. The compound exhibits high solubility in aqueous environments, facilitating rapid cellular uptake. Additionally, its stability in biological systems enables prolonged effects on metabolic processes, impacting cellular growth and differentiation. | ||||||
5-Iodotubercidin | 24386-93-4 | sc-3531 sc-3531A | 1 mg 5 mg | $150.00 $455.00 | 20 | |
5-Iodotubercidin is a selective inhibitor of adenosine kinase, exhibiting unique interactions with the enzyme's active site. Its structural similarity to adenosine allows it to effectively compete for binding, disrupting nucleotide metabolism. The compound's kinetic profile reveals a rapid onset of inhibition, significantly altering ATP levels within cells. Furthermore, its lipophilic nature enhances membrane permeability, promoting efficient cellular distribution and interaction with intracellular targets. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
Activates AMP-activated protein kinase (AMPK), potentially altering ADK activity by modulating adenine nucleotide levels. | ||||||
Adenosine Kinase Inhibitor Inhibitor | 214697-26-4 | sc-202900 | 5 mg | $434.00 | 9 | |
Adenosine Kinase Inhibitors are characterized by their ability to modulate adenosine signaling pathways through competitive inhibition of adenosine kinase. These compounds exhibit distinct binding affinities, often engaging in hydrogen bonding and hydrophobic interactions with the enzyme's active site. Their unique structural features can lead to altered reaction kinetics, influencing the phosphorylation of adenosine and impacting cellular energy homeostasis. Additionally, their solubility profiles facilitate diverse interactions within biological membranes, enhancing their functional versatility. | ||||||
2-Amino Adenosine | 2096-10-8 | sc-220693 sc-220693A | 25 mg 200 mg | $61.00 $122.00 | 1 | |
2-Amino Adenosine acts as a potent modulator of adenosine metabolism, exhibiting unique interactions with adenosine kinase. Its amino group enhances hydrogen bonding capabilities, promoting tighter binding to the enzyme's active site. This compound can alter the enzyme's conformational dynamics, leading to significant changes in reaction rates. Furthermore, its structural attributes influence solubility and membrane permeability, allowing for diverse biochemical interactions and regulatory effects within cellular environments. | ||||||
Dipyridamole | 58-32-2 | sc-200717 sc-200717A | 1 g 5 g | $30.00 $100.00 | 1 | |
Increases extracellular adenosine levels by inhibiting its reuptake, potentially affecting ADK activity. | ||||||
5-Acetyl-2-chloropyrazine | 160252-31-3 | sc-206979 | 500 mg | $300.00 | ||
5-Acetyl-2-chloropyrazine serves as a versatile building block in organic synthesis, exhibiting notable reactivity due to its electrophilic nature. The presence of the acetyl and chloropyrazine moieties facilitates nucleophilic attack, leading to diverse substitution reactions. Its unique electronic configuration enhances its ability to participate in cross-coupling reactions, while the chloropyrazine ring contributes to distinct steric effects, influencing reaction pathways and kinetics. Additionally, its polar characteristics can affect solubility in various solvents, impacting its reactivity in different environments. | ||||||
Theophylline | 58-55-9 | sc-202835 sc-202835A sc-202835B | 5 g 25 g 100 g | $20.00 $31.00 $83.00 | 6 | |
A nonselective phosphodiesterase inhibitor, increases intracellular cAMP levels, potentially influencing ADK activity. | ||||||
5′-Amino-5′-deoxyadenosine hydrochloride | 14365-44-7 | sc-284702 sc-284702A | 1 mg 5 mg | $204.00 $816.00 | ||
5'-Amino-5'-deoxyadenosine hydrochloride acts as a potent adenosine kinase (ADK) inhibitor, showcasing unique interactions with ATP and adenosine substrates. Its structural features promote specific binding affinities, influencing phosphorylation pathways. The compound's ability to modulate enzyme kinetics is notable, as it alters the rate of adenosine metabolism. Furthermore, its solubility profile enhances its reactivity in aqueous environments, facilitating diverse biochemical interactions. | ||||||
6-Chloro-7-deazapurine-β-D-riboside | 16754-80-6 | sc-221096 | 25 mg | $235.00 | ||
6-Chloro-7-deazapurine-β-D-riboside functions as an adenosine kinase (ADK) inhibitor, characterized by its unique structural conformation that allows for selective binding to the enzyme's active site. This compound exhibits distinct kinetic properties, influencing the phosphorylation dynamics of adenosine derivatives. Its interactions with nucleotide co-factors are pivotal, potentially altering metabolic flux and enzyme regulation. Additionally, its stability in various pH environments enhances its reactivity in biochemical assays. | ||||||