ACSF2 Activators
ACSF2 Activators are specialized chemicals that facilitate the activation of ACSF2 by targeting specific cellular pathways involved in fatty acid metabolism, mitochondrial biogenesis, and autophagy. For instance, Dibutyryl-cAMP elevates cAMP levels in the cell, leading to PKA activation. This chain of events culminates in the activation of ACSF2, particularly in pathways related to fatty acid metabolism. Metformin is another notable example; it activates AMP-activated protein kinase (AMPK), which in turn stimulates mitochondrial biogenesis, thereby activating ACSF2 within the context of energy metabolism.
The scope of ACSF2 Activators is far-reaching but decidedly targeted. Chemicals like Cilostazol inhibit PDE3, increasing cAMP levels, which lead to PKA and ACSF2 activation, specifically within the fatty acid synthesis pathway. Similarly, Spermidine induces autophagy by inhibiting EP300, subsequently boosting ACSF2 transcription and its involvement in fatty acid metabolism. These activators provide a critical arsenal for studying ACSF2's various roles within a cell, enabling scientists to delve deeper into understanding the protein's functional aspects.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
Elevates intracellular cAMP levels and activates PKA, leading to ACSF2 activation in fatty acid metabolism. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Activates AMPK, which then stimulates mitochondrial biogenesis and ACSF2 in energy metabolism. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AMPK activator that enhances mitochondrial function, contributing to ACSF2 activation. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
Stimulates sirtuins, impacting mitochondrial biogenesis and ACSF2 activation. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Induces autophagy by inhibiting EP300, which increases the transcription of ACSF2 involved in fatty acid metabolism. | ||||||
Cilostazol | 73963-72-1 | sc-201182 sc-201182A | 10 mg 50 mg | $107.00 $316.00 | 3 | |
Inhibits PDE3, raising cAMP levels, thereby activating PKA and ACSF2 in fatty acid synthesis. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Alters lysosomal pH and affects autophagy, impacting ACSF2 in fatty acid metabolism. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Inhibits phosphodiesterase, leading to increased cAMP and PKA activation, which subsequently activates ACSF2. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Activates PPAR-γ, impacting fatty acid metabolism and contributing to ACSF2 activation. | ||||||
Fasudil, Monohydrochloride Salt | 105628-07-7 | sc-203418 sc-203418A sc-203418B sc-203418C sc-203418D sc-203418E sc-203418F | 10 mg 50 mg 250 mg 1 g 2 g 5 g 10 g | $18.00 $32.00 $85.00 $165.00 $248.00 $486.00 $910.00 | 5 | |
Inhibits Rho kinase, leading to increased nitric oxide bioavailability, impacting endothelial function and indirectly stimulating ACSF2 in fatty acid metabolism. | ||||||