A33 Activators
A33 Activators represent a diverse group of compounds that indirectly enhance the functionality of A33, predominantly in the context of cell adhesion and signaling within the gastrointestinal tract. Trifluoperazine and Thapsigargin, by modulating calcium signaling pathways, indirectly enhance the activity of A33 in cell adhesion and intercellular communication, crucial in maintaining the integrity of the intestinal epithelium. Butyrate, through its role in histone deacetylase inhibition, affects gene expression, thereby supporting A33's function in gut epithelial integrity. Similarly, Genistein and 5-Fluorouracil, by influencing cell signaling and DNA synthesis, respectively, contribute to enhancing A33's role in the gastrointestinal tissue, particularly in processes like cell turnover and adhesion.
Additionally, compounds like Sulindac, Rapamycin, and Curcumin play significant roles in modulating various pathways that indirectly enhance A33's activity. Sulindac, by affecting COX pathways, and Curcumin, through NF-κB signaling modulation, both contribute to the regulation of inflammation and cell adhesion, processes where A33 is actively involved. Rapamycin, an mTOR inhibitor, impacts cell growth and proliferation, thus supporting A33's function in these areas. Furthermore, natural compounds like Resveratrol, Quercetin, Berberine, and Epigallocatechin gallate (EGCG) add to this enhancement by influencing sirtuin activation, inflammatory pathways, metabolic and signaling processes. These diverse mechanisms collectively support the critical role of A33 in maintaining intestinal epithelium integrity and function, highlighting the intricate network of biochemical processes and signaling pathways that contribute to the modulation of A33 activity in the gastrointestinal tract.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin, a SERCA pump inhibitor, disrupts calcium homeostasis. This disruption indirectly enhances A33 activity by influencing calcium-dependent signaling pathways, which are crucial for cell adhesion and intercellular communication, processes where A33 is actively involved in gut epithelium. | ||||||
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $63.00 $174.00 | ||
Butyrate, a short-chain fatty acid, modulates gene expression through histone deacetylase inhibition. This modulation indirectly enhances the functional activity of A33 in the gastrointestinal tract by influencing the expression of genes involved in cell adhesion and gut epithelial integrity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, affects cell signaling. By modulating tyrosine kinase activity, it indirectly enhances A33's role in cell signaling and adhesion in gastrointestinal tissues, as A33 is involved in these processes within the intestinal epithelium. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
5-Fluorouracil, an antimetabolite, impacts DNA synthesis and repair. By affecting these processes, it indirectly enhances A33's role in maintaining intestinal epithelium integrity and function, as A33 is closely associated with cell turnover and adhesion in the gut. | ||||||
Sulindac | 38194-50-2 | sc-202823 sc-202823A sc-202823B | 1 g 5 g 10 g | $31.00 $84.00 $147.00 | 3 | |
Sulindac, a nonsteroidal anti-inflammatory drug, modulates COX pathways. This modulation indirectly enhances A33's activity in the gastrointestinal tract by influencing pathways involved in inflammation and cell adhesion, processes where A33 plays a significant role. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin, an mTOR inhibitor, affects cell growth and proliferation. By inhibiting mTOR, it indirectly enhances A33's function in cell signaling and adhesion within the gastrointestinal tract, as A33 is involved in these processes, particularly in the context of cell growth regulation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, an anti-inflammatory compound, modulates NF-κB signaling. By influencing this pathway, it indirectly enhances A33's role in gastrointestinal tissue integrity and cell adhesion, as A33 is significantly involved in these processes in the intestinal epithelium. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenol, influences several signaling pathways, including sirtuin activation. This modulation indirectly enhances A33's activity in cell adhesion and signaling in the gastrointestinal tract, as A33 plays a crucial role in these processes within the gut epithelium. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid, has anti-inflammatory effects. By modulating inflammatory signaling pathways, it indirectly enhances A33's functional activity in maintaining intestinal epithelial integrity and cell adhesion, as A33 is actively involved in these processes in the gut. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine, an alkaloid, modulates metabolic and inflammatory pathways. By influencing these pathways, it indirectly enhances A33's role in cell signaling and adhesion in the gastrointestinal tract, particularly in the context of gut epithelium integrity and function. | ||||||