The chemical class known as A1BG inhibitors belongs to the broader category of molecules designed to modulate the activity of the A1BG protein. A1BG, short for Alpha-1-B glycoprotein, is a glycoprotein encoded by the A1BG gene in humans. This protein plays a crucial role in various physiological processes, including immune response regulation, cell adhesion, and inflammation. A1BG inhibitors are specifically designed to interact with A1BG, aiming to disrupt or attenuate its normal function within these cellular processes.
The development of A1BG inhibitors often involves the design and synthesis of small molecules that can selectively bind to the A1BG protein, thereby influencing its activity. The molecular interactions between the inhibitor and A1BG may involve specific binding sites on the protein surface, leading to conformational changes that alter its functional properties. The rationale behind designing A1BG inhibitors is rooted in the desire to explore and understand the intricate biochemical pathways in which A1BG participates. By selectively modulating A1BG, researchers aim to unravel its roles in different cellular contexts, shedding light on potential implications for basic biology and offering insights into the complex interplay of proteins within these intricate networks. The development and study of A1BG inhibitors contribute to the broader scientific understanding of molecular pathways and may pave the way for further investigations into the functional significance of A1BG in health and disease.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sulfasalazine | 599-79-1 | sc-204312 sc-204312A sc-204312B sc-204312C | 1 g 2.5 g 5 g 10 g | $60.00 $75.00 $125.00 $205.00 | 8 | |
This compound can interfere with the NF-κB pathway, which might regulate the expression of A1BG. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
As a flavonoid, quercetin can modulate various signaling pathways that could alter A1BG activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin affects multiple cellular processes and could modulate A1BG expression indirectly. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
It is an isoflavone that may impact cell signaling pathways potentially affecting A1BG. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
This polyphenol can modulate anti-inflammatory pathways, possibly influencing A1BG. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This catechin can alter numerous signaling pathways and could affect A1BG indirectly. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
As an HDAC inhibitor, it can alter gene expression and potentially modulate A1BG levels. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can affect various signaling pathways, possibly impacting A1BG expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
It inhibits mTOR signaling and could have an indirect effect on A1BG activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
As an inhibitor of MEK, it might influence signaling pathways associated with A1BG. | ||||||