5730419I09Rik Inhibitors
Chemicals classified as C2cd5 Inhibitors would encompass a variety of compounds that indirectly influence the functionality of the C2 calcium-dependent domain containing 5 protein by modulating calcium signaling or homeostasis, which are essential for the activity of proteins with C2 domains. Verapamil and Nifedipine, for instance, can prevent the influx of calcium through voltage-gated calcium channels, potentially reducing the availability of calcium necessary for the function of C2 domain proteins like C2cd5. Dantrolene and Ryanodine, on the other hand, act on the sarcoplasmic reticulum to inhibit the release of calcium, thereby possibly affecting the activation and function of C2cd5.
Compounds such as Thapsigargin and Cyclopiazonic Acid target the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase, disrupting the sequestration and release of calcium within the cell, which could alter the function of C2cd5. BAPTA-AM and TMB-8 are intracellular calcium chelators that sequester calcium, thus potentially preventing the binding of calcium to C2cd5, impairing its function. SKF-96365 and 2-APB are known to influence calcium entry and signaling in the cell, which could indirectly modulate the activity of C2cd5. W-7, as a calmodulin antagonist, can disrupt downstream calcium signaling pathways, potentially affecting proteins that are regulated by calmodulin-dependent pathways, including C2cd5. Finally, A23187 is a calcium ionophore that disrupts normal calcium gradients across membranes and can drastically affect cellular calcium homeostasis, possibly influencing the function of C2 domain-containing proteins like C2cd5.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
Blocks calcium channels, potentially altering calcium-dependent processes that C2cd5 is involved in. | ||||||
Dantrolene | 7261-97-4 | sc-500165 | 25 mg | $350.00 | 7 | |
Interferes with calcium release from the sarcoplasmic reticulum, which can affect C2 domain proteins. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Inhibits the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA), which can disrupt calcium homeostasis affecting C2cd5 activity. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $458.00 | 61 | |
Calcium chelator that can sequester intracellular calcium, potentially affecting C2 domain-mediated functions. | ||||||
TMB-8 • HCl | 53464-72-5 | sc-3522 sc-3522A | 10 mg 50 mg | $43.00 $129.00 | 10 | |
Inhibits intracellular calcium release, which can affect proteins requiring calcium for their function. | ||||||
SK&F 96365 | 130495-35-1 | sc-201475 sc-201475B sc-201475A sc-201475C | 5 mg 10 mg 25 mg 50 mg | $103.00 $158.00 $397.00 $656.00 | 2 | |
Inhibitor of receptor-mediated calcium entry, which can influence C2 domain-containing proteins. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $28.00 $53.00 | 37 | |
Modulates calcium signaling through various mechanisms, potentially influencing C2 domain protein activity. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
Blocks L-type calcium channels, potentially affecting calcium signaling involved in C2 domain protein function. | ||||||
Ryanodine | 15662-33-6 | sc-201523 sc-201523A | 1 mg 5 mg | $223.00 $799.00 | 19 | |
Modulates the release of calcium from sarcoplasmic reticulum, which can influence C2 domain proteins. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $166.00 $306.00 $1675.00 | 18 | |
Calmodulin antagonist that can affect calcium signaling pathways, potentially influencing C2cd5. | ||||||