The chemical class of Tektip1 Inhibitors encompasses a diverse group of compounds that have the capacity to indirectly affect the Tektip1 protein by targeting various cellular processes and signaling pathways. Microtubule-targeting agents, such as Colchicine, Nocodazole, Taxol, and 2-Methoxyestradiol, can disrupt the normal dynamics of microtubules, which are fundamental components of the cellular cytoskeleton. Since Tektip1 may be involved with microtubule functions, altering the stability or polymerization of microtubules can influence Tektip1 interactions and functions within the cell. Withaferin A, targeting another cytoskeletal component, vimentin, also falls within this category, as changes in vimentin organization can impact cellular mechanisms that Tektip1 might be a part of.
Additionally, compounds that modulate intracellular signaling such as Forskolin, LY294002, Wortmannin, PD98059, and SB203580 can affect various pathways including cAMP pathways, PI3K signaling, and MAPK/ERK pathways. These pathways can regulate a wide array of cellular functions, and Tektip1's role within these processes can be influenced by such inhibitors. Furthermore, Blebbistatin and ML-7, which target myosin II ATPase and myosin light chain kinase respectively, can affect cytoskeletal tension and contractility, potentially impacting the interaction and function of Tektip1 in cellular motility and structure maintenance.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Binds to tubulin, inhibiting microtubule polymerization, which can affect cellular processes where Tektip1 is involved. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Destabilizes microtubules, which could alter Tektip1 associated functions in cell structure and motility. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Stabilizes microtubules, which can disrupt normal microtubule dynamics essential for Tektip1 interactions. | ||||||
Withaferin A | 5119-48-2 | sc-200381 sc-200381A sc-200381B sc-200381C | 1 mg 10 mg 100 mg 1 g | $127.00 $572.00 $4090.00 $20104.00 | 20 | |
Inhibits vimentin, a cytoskeletal component, which can interfere with cellular mechanisms involving Tektip1. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can affect intracellular signaling, possibly impacting Tektip1-related pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor that can disrupt signaling pathways and possibly affect those involving Tektip1. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK1, which can alter the MAPK/ERK pathway and possibly Tektip1's role within this pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor that can modify inflammatory response signaling, potentially impacting Tektip1. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $71.00 $260.00 $485.00 $949.00 | ||
Inhibits myosin II ATPase activity, which can influence cytoskeletal dynamics and potentially Tektip1 interaction. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $89.00 $262.00 | 13 | |
Inhibits myosin light chain kinase, affecting cytoskeletal tension and potentially Tektip1's function. | ||||||