The class of 4921501E09Rik inhibitors comprises a diverse array of compounds that exert their effects by directly or indirectly modulating signaling pathways associated with cellular processes. While specific inhibitors directly targeting 4921501E09Rik may be limited, the compounds selected influence cellular functions through pathways interconnected with 4921501E09Rik. One group of inhibitors includes SB-203580, U0126, PD98059, and SB-218078, which target various components of the MAPK signaling pathways such as p38 and MEK1. SB-203580 directly inhibits p38 MAPK, impacting stress responses and cellular processes. U0126 and PD98059 target MEK1, influencing the MAPK/ERK pathway. SB-218078 modulates JNK, affecting stress responses. The interconnected nature of these pathways with diverse cellular functions suggests that these inhibitors can indirectly influence 4921501E09Rik by altering shared signaling cascades.
Another set of inhibitors, including Wortmannin, LY294002, and GSK-690693, target the PI3K/AKT pathway. Wortmannin and LY294002 directly inhibit PI3K, disrupting downstream signaling. GSK-690693 targets AKT. The PI3K/AKT pathway is central to various cellular processes, and inhibitors of this pathway can indirectly influence 4921501E09Rik by disrupting interconnected signaling networks governing cellular functions. Additionally, SP600125, a JNK inhibitor, directly modulates the JNK pathway, impacting stress responses and apoptosis. This inhibitor can indirectly influence 4921501E09Rik through cross-regulation with other signaling pathways associated with diverse cellular processes. In conclusion, while direct inhibitors of 4921501E09Rik may be limited, the selected compounds, through their modulation of interconnected signaling pathways, offer potential indirect avenues to influence the cellular functions associated with 4921501E09Rik. The diverse mechanisms of action of these inhibitors provide valuable tools for investigating the intricate regulatory networks governing cellular processes and their potential connections to 4921501E09Rik.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor. SB-203580 directly modulates the MAPK signaling pathway by inhibiting p38, a kinase associated with cellular stress responses. This inhibition can indirectly affect 4921501E09Rik, as p38 MAPK regulates various cellular processes. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor. Wortmannin directly targets the PI3K pathway, affecting downstream signaling cascades. Given the crosstalk between PI3K and various cellular processes, Wortmannin may indirectly influence 4921501E09Rik through its impact on interconnected signaling networks. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor. SP600125 directly modulates the JNK pathway, affecting stress responses and apoptosis. The indirect impact on 4921501E09Rik may occur through the cross-regulation between JNK and other signaling pathways involved in diverse cellular processes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor. LY294002 directly influences the PI3K pathway, disrupting downstream signaling. The interconnected nature of PI3K signaling with various cellular processes can lead to indirect modulation of 4921501E09Rik through the disruption of shared signaling cascades. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A MEK1 inhibitor. PD98059 directly targets the MAPK/ERK pathway by inhibiting MEK1, impacting downstream signaling. The interconnection of the MAPK/ERK pathway with diverse cellular functions allows PD98059 to potentially influence 4921501E09Rik indirectly through shared signaling pathways. | ||||||
SB 218078 | 135897-06-2 | sc-203692 | 1 mg | $133.00 | 1 | |
A JNK inhibitor. SB-218078 directly modulates the JNK pathway, impacting stress responses and apoptosis. The indirect influence on 4921501E09Rik may occur through the interconnected signaling networks associated with JNK and other pathways governing various cellular processes. | ||||||
Akt Inhibitor IV | 681281-88-9 | sc-203809 sc-203809A | 5 mg 25 mg | $173.00 $695.00 | 42 | |
An AKT inhibitor. AKT Inhibitor IV directly targets the PI3K/AKT pathway, affecting downstream signaling. Given the central role of PI3K/AKT in cellular processes, this inhibitor may indirectly modulate 4921501E09Rik through its impact on shared signaling cascades and regulatory networks. | ||||||
GSK 690693 | 937174-76-0 | sc-363280 sc-363280A | 10 mg 50 mg | $255.00 $1071.00 | 4 | |
An AKT inhibitor. GSK-690693 directly influences the PI3K/AKT pathway, impacting downstream signaling. The interconnected nature of PI3K/AKT signaling with various cellular processes allows GSK-690693 to potentially influence 4921501E09Rik indirectly through shared signaling cascades. | ||||||
LY 303511 | 154447-38-8 | sc-202215 sc-202215A | 1 mg 5 mg | $66.00 $273.00 | 3 | |
A PI3K inhibitor. LY303511 directly influences the PI3K pathway, disrupting downstream signaling. The interconnected nature of PI3K signaling with various cellular processes allows LY303511 to potentially influence 4921501E09Rik indirectly through its impact on shared signaling cascades. | ||||||