4.1R Inhibitors
The chemical class of 4.1R inhibitors encompasses a range of compounds that indirectly modulate the function of 4.1R, a protein critical for cytoskeletal integrity and cell membrane stability. These inhibitors do not target 4.1R directly but influence the cellular structures and signaling pathways associated with 4.1R's function. The primary mode of action for these inhibitors involves targeting the cytoskeletal elements, such as actin and microtubules, and related signaling pathways, thereby impacting the conditions under which 4.1R operates.
Compounds like Phalloidin and Cytochalasin D interact with actin filaments, either stabilizing or disrupting them, thus affecting the interaction of 4.1R with the cytoskeleton. Similarly, microtubule-affecting agents like Nocodazole and Colchicine can alter 4.1R's interactions with the cytoskeleton by modulating microtubule dynamics. Myosin inhibitors such as Blebbistatin and ML-7 can also indirectly influence 4.1R's role in cytoskeletal organization due to the interplay between actin filaments and myosin. Additionally, compounds like Forskolin, which affects adenylate cyclase, can modulate signaling pathways that potentially influence 4.1R function.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Phalloidin | 17466-45-4 | sc-202763 | 1 mg | $234.00 | 33 | |
Stabilizes actin filaments, potentially affecting the interaction between 4.1R and the cytoskeleton. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Disrupts actin polymerization, possibly impacting 4.1R's role in cytoskeletal organization. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Binds to actin monomers, potentially altering 4.1R's interactions with the actin cytoskeleton. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Disrupts microtubule dynamics, possibly influencing 4.1R's role in cell structure and signaling. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Binds to tubulin, potentially affecting 4.1R's interaction with the cytoskeleton. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules, might impact the functional dynamics of 4.1R in the cell. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Inhibits microtubule assembly, could affect 4.1R's role in cytoskeletal structure. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
Inhibits myosin II, potentially affecting 4.1R's role in cytoskeletal interactions. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor, might influence 4.1R's function in cytoskeletal organization. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Inhibits myosin light chain kinase, potentially impacting 4.1R's interactions with the actin cytoskeleton. | ||||||