1700010I14Rik Activators
1700010I14Rik Protein activators comprise chemical compounds that engage with and enhance the functionality of this protein through various biochemical pathways. Forskolin catalyzes the activation of adenylyl cyclase, thereby raising intracellular cAMP levels that activate PKA, which can phosphorylate substrates affecting the 1700010I14Rik Protein's activity. Similarly, IBMX impedes phosphodiesterase activity, sustaining increased cAMP and cGMP concentrations that potentiate PKA signaling, potentially culminating in the phosphorylation and enhancement of 1700010I14Rik Protein. Epigallocatechin Gallate (EGCG) inhibits specific kinases, indirectly leading to the activation of 1700010I14Rik Protein by reducing inhibitory phosphorylations. RAI14 Activators encompass a diverse array of chemical compounds that indirectly boost the functional activity of RAI14, primarily through modulation of intracellular signaling pathways. Forskolin, by escalating intracellular cAMP, activates protein kinase A (PKA), which is known to phosphorylate proteins involved in cell adhesion, a process where RAI14 is implicated.
Similarly, Ionomycin, by increasing intracellular calcium levels, can stimulate calcium-dependent signaling mechanisms, affecting RAI14's role in cellular adhesion. Isoproterenol also raises cAMP levels, thereby activating PKA and potentially influencing RAI14's activity in adhesion and signaling. PMA acts on protein kinase C (PKC), a key player in cell adhesion, therefore possibly enhancing RAI14's involvement in this cellular function. EGCG, by inhibiting specific kinases, has the potential to alleviate suppressive effects on the pathways that RAI14 modulates, particularly in cell-matrix interactions. Continuing with the theme of pathway modulation, Sphingosine-1-phosphate (S1P) mediates its effects through G protein-coupled receptors that could activate signaling cascades relevant to RAI14's adhesion functions. LY294002 and Wortmannin, both PI3K inhibitors, may boost RAI14 activity by modifying signaling pathways that intersect with cell adhesion processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a nonspecific inhibitor of phosphodiesterases, which prevents the breakdown of cAMP and cGMP, thereby indirectly enhancing the signaling pathways that rely on these cyclic nucleotides, potentially increasing the functional activity of 1700010I14Rik Protein. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a potent antioxidant polyphenol that can modulate kinase activity. By inhibiting certain kinases, EGCG could shift signaling pathways to favor the activation and function of 1700010I14Rik Protein. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a diacylglycerol analogue that activates protein kinase C (PKC). Through PKC activation, PMA influences signaling pathways that could enhance the activity of 1700010I14Rik Protein by post-translational modifications. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
S1P binds to its G-protein coupled receptors, initiating downstream signaling that could involve the activation of 1700010I14Rik Protein through altered cytoskeletal dynamics or other mechanisms. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, triggering calcium-dependent signaling pathways which might lead to the activation of 1700010I14Rik Protein. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride inhibits glycogen synthase kinase-3 (GSK-3). Inhibition of GSK-3 could lead to the activation of signaling pathways that may indirectly enhance the functional activity of 1700010I14Rik Protein. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
NAD+ is involved in redox reactions, serving as an electron transporter. Increased availability of NAD+ can influence signaling pathways such as sirtuin activation, which could enhance the function of 1700010I14Rik Protein indirectly. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid regulates gene expression through retinoic acid receptors and can influence cell differentiation pathways, potentially leading to enhanced activity of 1700010I14Rik Protein. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate is a histone deacetylase inhibitor that can affect chromatin structure and gene expression. It may indirectly enhance the functional activity of 1700010I14Rik Protein by altering the expression of interacting proteins or signaling components. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a DNA methyltransferase inhibitor that can lead to DNA demethylation and alter gene expression patterns. This could result in an indirect enhancement of 1700010I14Rik Protein activity by changing the expression of proteins in its signaling network. | ||||||