1110015M06Rik Inhibitors
The chemical class of 1110015M06Rik inhibitors encompasses compounds that modulate key signaling pathways crucial for the regulation of cellular processes associated with 1110015M06Rik. These inhibitors act through diverse mechanisms, impacting intracellular signaling cascades and cellular functions.
Forskolin, A23187, and PMA represent the diverse approaches employed by 1110015M06Rik inhibitors. Forskolin activates adenylyl cyclase, leading to increased cAMP and subsequent PKA activation. A23187, a calcium ionophore, elevates intracellular calcium levels, influencing calcium-dependent pathways. PMA activates PKC, impacting downstream signaling involved in cell growth and apoptosis.
Furthermore, IBMX, Bay K 8644, and 8-Br-cAMP modulate cAMP levels and activate PKA, while Dibutyryl cGMP activates PKG, influencing cGMP/PKG signaling. Rolipram inhibits PDE4, increasing cAMP levels. Calyculin A, a protein phosphatase inhibitor, affects phosphorylation-dependent pathways, and NS1619 activates BK channels, involved in membrane potential regulation. Thapsigargin elevates intracellular calcium by inhibiting SERCA. This diverse array of inhibitors collectively provides insights into potential targets for modulating cellular processes associated with 1110015M06Rik.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 is a calcium ionophore that facilitates calcium influx into cells. Increased intracellular calcium levels can modulate various signaling pathways. The activation of calcium-dependent pathways may influence cellular processes associated with 1110015M06Rik, as calcium signaling participates in diverse cellular functions. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), a key signaling molecule. PKC activation can impact multiple cellular processes. The influence on PKC-related pathways may affect cellular functions associated with 1110015M06Rik, as PKC participates in the regulation of cell growth, differentiation, and apoptosis. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX inhibits phosphodiesterases, leading to increased cAMP levels. Elevated cAMP can activate PKA, influencing downstream signaling pathways. The activation of cAMP/PKA signaling may impact cellular processes associated with 1110015M06Rik as cAMP signaling is involved in diverse cellular functions. | ||||||
(±)-Bay K 8644 | 71145-03-4 | sc-203324 sc-203324A sc-203324B | 1 mg 5 mg 50 mg | $82.00 $192.00 $801.00 | ||
Bay K 8644 is a calcium channel activator, leading to increased calcium influx. Elevated intracellular calcium levels can modulate various signaling pathways. The activation of calcium-dependent pathways may influence cellular processes associated with 1110015M06Rik, as calcium signaling participates in diverse cellular functions. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
8-Br-cAMP is a cell-permeable analog of cAMP that can activate PKA. PKA activation can influence downstream signaling pathways. The activation of cAMP/PKA signaling may impact cellular processes associated with 1110015M06Rik, as cAMP signaling is involved in diverse cellular functions. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin facilitates calcium influx into cells, leading to increased intracellular calcium levels. The activation of calcium-dependent pathways may influence cellular processes associated with 1110015M06Rik, as calcium signaling participates in diverse cellular functions. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram inhibits phosphodiesterase 4 (PDE4), leading to increased cAMP levels. Elevated cAMP can activate PKA, influencing downstream signaling pathways. The activation of cAMP/PKA signaling may impact cellular processes associated with 1110015M06Rik, as cAMP signaling is involved in diverse cellular functions. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $160.00 $750.00 | 59 | |
Calyculin A is a potent protein phosphatase inhibitor, leading to increased phosphorylation levels. The inhibition of protein phosphatases may influence multiple signaling pathways. The impact on phosphorylation-dependent pathways may affect cellular functions associated with 1110015M06Rik, as phosphorylation is a key regulatory mechanism. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
NS1619 is a large-conductance calcium-activated potassium channel (BK channel) activator. Activation of BK channels may modulate cellular processes associated with 1110015M06Rik, as these channels are involved in the regulation of membrane potential, calcium signaling, and cellular excitability. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin inhibits SERCA (sarco/endoplasmic reticulum calcium ATPase), leading to increased intracellular calcium levels. The activation of calcium-dependent pathways may influence cellular processes associated with 1110015M06Rik, as calcium signaling participates in diverse cellular functions. | ||||||