Date published: 2026-6-2

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TRPC Antibodies

Santa Cruz Biotechnology features a diverse variety of TRPC monoclonal antibodies for research focused on understanding transient receptor potential channels. TRPC monoclonal antibodies are compatible with multiple experimental techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Transient receptor potential channels, or TRPCs, are integral membrane proteins that play a crucial role in various physiological processes, including calcium signaling, sensory perception, and cellular homeostasis. TRPC dysregulation has been implicated in numerous diseases, making TRPCs significant targets for therapeutic intervention and research. Understanding the function and regulation of TRPCs can provide insights into their contributions to health and disease. TRPC monoclonal antibodies enable precise detection and characterization of TRPC proteins across diverse experimental applications. Researchers can explore TRPC signaling pathways through detailed molecular analysis and functional studies. TRPC monoclonal antibodies from Santa Cruz Biotechnology support the scientific community in advancing our understanding of cellular signaling mechanisms and potential therapeutic approaches.

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TRPC Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TRPC1 Antibody (E-6)

sc-133076mouse IgG1 κ689-793 (h)WB, IP, IF, IHC(P), ELISAm, r, h
45
(17)

TRPC3 Antibody (C-5)

sc-514670mouse IgG2a κ1-100 (h)WB, IP, IF, ELISAm, r, h
10
(8)

TRPC5 Antibody (1C8)

sc-293259mouse IgG2a κ534-603 (h)WB, IP, ELISAm, r, h
3
(1)

TRPC6 Antibody (B-10)

sc-515837mouse IgG1 κ546-590 (h)WB, IP, IF, ELISAm, r, h
11
(3)

TRPC6 Antibody (E-7)

sc-515927mouse IgG1838-857 (h)WB, IP, IF, ELISAh

new

(0)

TRPC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TRPC1 Double Nickase Plasmid (h)

sc-401040-NIChGene KnockoutPuromycin0
(0)

TRPC1 Double Nickase Plasmid (h2)

sc-401040-NIC-2hGene KnockoutPuromycin0
(0)

TRPC1 CRISPR/Cas9 KO Plasmid (m2)

sc-423512-KO-2mGene KnockoutGFP0
(0)

TRPC1 HDR Plasmid (m2)

sc-423512-HDR-2mHomology Directed RepairPuromycin0
(0)

TRPC1 Double Nickase Plasmid (m)

sc-423512-NICmGene KnockoutPuromycin0
(0)

TRPC1 Double Nickase Plasmid (m2)

sc-423512-NIC-2mGene KnockoutPuromycin0
(0)

TRPC2 CRISPR/Cas9 KO Plasmid (m)

sc-423513mGene KnockoutGFP0
(0)

TRPC3 CRISPR/Cas9 KO Plasmid (m2)

sc-423514-KO-2mGene KnockoutGFP0
(0)

TRPC4 CRISPR/Cas9 KO Plasmid (m)

sc-423515mGene KnockoutGFP0
(0)

TRPC5 Double Nickase Plasmid (h)

sc-403745-NIChGene KnockoutPuromycin0
(0)

TRPC5 Double Nickase Plasmid (h2)

sc-403745-NIC-2hGene KnockoutPuromycin0
(0)

TRPC5 CRISPR/Cas9 KO Plasmid (m)

sc-423516mGene KnockoutGFP0
(0)

TRPC6 CRISPR/Cas9 KO Plasmid (h)

sc-401205hGene KnockoutGFP0
(0)

TRPC6 HDR Plasmid (h2)

sc-401205-HDR-2hHomology Directed RepairPuromycin0
(0)

TRPC6 Double Nickase Plasmid (h)

sc-401205-NIChGene KnockoutPuromycin0
(0)

TRPC6 Double Nickase Plasmid (h2)

sc-401205-NIC-2hGene KnockoutPuromycin0
(0)

TRPC6 CRISPR/Cas9 KO Plasmid (m)

sc-423517mGene KnockoutGFP0
(0)

TRPC6 HDR Plasmid (m)

sc-423517-HDRmHomology Directed RepairPuromycin0
(0)

TRPC6 Double Nickase Plasmid (m)

sc-423517-NICmGene KnockoutPuromycin0
(0)

TRPC6 Double Nickase Plasmid (m2)

sc-423517-NIC-2mGene KnockoutPuromycin0
(0)

TRPC3/6/7 CRISPR/Cas9 KO Plasmid (h)

sc-403740hGene KnockoutGFP0
(0)

TRPC3/6/7 Double Nickase Plasmid (h)

sc-403740-NIChGene KnockoutPuromycin0
(0)

TRPC3/6/7 Double Nickase Plasmid (h2)

sc-403740-NIC-2hGene KnockoutPuromycin0
(0)

TRPC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TRPC1 CRISPR Activation Plasmid (h)

sc-401040-ACThGene ActivationPuro, Blast, Hygro0
(0)

TRPC5 CRISPR Activation Plasmid (h)

sc-403745-ACThGene ActivationPuro, Blast, Hygro0
(0)

TRPC6 CRISPR Activation Plasmid (h)

sc-401205-ACThGene ActivationPuro, Blast, Hygro0
(0)

TRPC6 CRISPR Activation Plasmid (h2)

sc-401205-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

TRPC6 CRISPR Activation Plasmid (m)

sc-423517-ACTmGene ActivationPuro, Blast, Hygro0
(0)

TRPC6 CRISPR Activation Plasmid (m2)

sc-423517-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

TRPC7 CRISPR Activation Plasmid (h)

sc-403911-ACThGene ActivationPuro, Blast, Hygro0
(0)

TRPC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TRPC1 siRNA (h)

sc-42664hGene SilencingN/A
15
(1)

TRPC1 shRNA Plasmid (h)

sc-42664-SHhGene SilencingPuromycin
15
(1)

TRPC1 shRNA (h) Lentiviral Particles

sc-42664-VhGene SilencingPuromycin
15
(1)

TRPC1 siRNA (m)

sc-42665mGene SilencingN/A
10
(0)

TRPC1 shRNA Plasmid (m)

sc-42665-SHmGene SilencingPuromycin
10
(0)

TRPC1 shRNA (m) Lentiviral Particles

sc-42665-VmGene SilencingPuromycin
10
(0)

TRPC1 siRNA (r)

sc-61872rGene SilencingN/A0
(0)

TRPC1 shRNA Plasmid (r)

sc-61872-SHrGene SilencingPuromycin0
(0)

TRPC1 shRNA (r) Lentiviral Particles

sc-61872-VrGene SilencingPuromycin0
(0)

TRPC2 siRNA (m)

sc-154691mGene SilencingN/A0
(0)

TRPC2 shRNA Plasmid (m)

sc-154691-SHmGene SilencingPuromycin0
(0)

TRPC2 shRNA (m) Lentiviral Particles

sc-154691-VmGene SilencingPuromycin0
(0)

TRPC3 siRNA (h)

sc-42666hGene SilencingN/A
6
(1)

TRPC3 shRNA Plasmid (h)

sc-42666-SHhGene SilencingPuromycin
6
(1)

TRPC3 shRNA (h) Lentiviral Particles

sc-42666-VhGene SilencingPuromycin
6
(1)

TRPC3 siRNA (m)

sc-42667mGene SilencingN/A
3
(0)

TRPC3 shRNA Plasmid (m)

sc-42667-SHmGene SilencingPuromycin
3
(0)

TRPC3 shRNA (m) Lentiviral Particles

sc-42667-VmGene SilencingPuromycin
3
(0)

TRPC4 siRNA (h)

sc-42668hGene SilencingN/A
4
(0)

TRPC4 shRNA Plasmid (h)

sc-42668-SHhGene SilencingPuromycin
4
(0)

TRPC4 shRNA (h) Lentiviral Particles

sc-42668-VhGene SilencingPuromycin
4
(0)

TRPC4 siRNA (m)

sc-42669mGene SilencingN/A
4
(0)

TRPC4 shRNA Plasmid (m)

sc-42669-SHmGene SilencingPuromycin
4
(0)

TRPC4 shRNA (m) Lentiviral Particles

sc-42669-VmGene SilencingPuromycin
4
(0)

TRPC5 siRNA (h)

sc-42670hGene SilencingN/A
9
(0)

TRPC5 shRNA Plasmid (h)

sc-42670-SHhGene SilencingPuromycin
9
(0)

TRPC5 shRNA (h) Lentiviral Particles

sc-42670-VhGene SilencingPuromycin
9
(0)

TRPC5 siRNA (m)

sc-42671mGene SilencingN/A
1
(0)

TRPC5 shRNA Plasmid (m)

sc-42671-SHmGene SilencingPuromycin
1
(0)

TRPC5 shRNA (m) Lentiviral Particles

sc-42671-VmGene SilencingPuromycin
1
(0)

TRPC6 siRNA (h)

sc-42672hGene SilencingN/A
15
(0)

TRPC6 shRNA Plasmid (h)

sc-42672-SHhGene SilencingPuromycin
15
(0)

TRPC6 shRNA (h) Lentiviral Particles

sc-42672-VhGene SilencingPuromycin
15
(0)

TRPC6 siRNA (m)

sc-42673mGene SilencingN/A
8
(0)

TRPC6 shRNA Plasmid (m)

sc-42673-SHmGene SilencingPuromycin
8
(0)

TRPC6 shRNA (m) Lentiviral Particles

sc-42673-VmGene SilencingPuromycin
8
(0)

TRPC7 siRNA (h)

sc-106641hGene SilencingN/A
2
(0)

TRPC7 shRNA Plasmid (h)

sc-106641-SHhGene SilencingPuromycin
2
(0)

TRPC7 shRNA (h) Lentiviral Particles

sc-106641-VhGene SilencingPuromycin
2
(0)

TRPC7 siRNA (m)

sc-154693mGene SilencingN/A0
(0)

TRPC7 shRNA Plasmid (m)

sc-154693-SHmGene SilencingPuromycin0
(0)

TRPC7 shRNA (m) Lentiviral Particles

sc-154693-VmGene SilencingPuromycin0
(0)

TRPD52L3 siRNA (m)

sc-154694mGene SilencingN/A0
(0)

TRPD52L3 shRNA Plasmid (m)

sc-154694-SHmGene SilencingPuromycin0
(0)

TRPD52L3 shRNA (m) Lentiviral Particles

sc-154694-VmGene SilencingPuromycin0
(0)